MFS transporter [Escherichia coli].

LOCUS       WP_001279690             467 aa            linear   BCT 28-JUL-2024
ACCESSION   WP_001279690
VERSION     WP_001279690.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 467)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 467)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 467)
  AUTHORS   Yan,N.
  TITLE     Structural advances for the major facilitator superfamily (MFS)
            transporters
  JOURNAL   Trends Biochem Sci 38 (3), 151-159 (2013)
   PUBMED   23403214
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11489668
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..467
                     /product="MFS transporter"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=51381
     Region          16..451
                     /region_name="gph"
                     /note="sugar (Glycoside-Pentoside-Hexuronide) transporter;
                     TIGR00792"
                     /db_xref="CDD:273270"
ORIGIN      
        1 msdhnpltlk lnlrekiayg mgdvgsnlml sigtlyllkf ytdelgmpay yggiiflvak
       61 fftaftdmlt gflldsrkni gpkgkfrpfi lyaavpaali atlqfiattf slpvkttiat
      121 alfmmfglsy slmncsygam ipaitknpne raqlaayrqg gatigllict vafiplqslf
      181 sdstvgyaca almfsiggfi fmmlcyrgvk ehyvdtaptg hkasilksfc aifrnppllv
      241 lcianlctla afniklaiqv yytqyvlndi nllswmgffs mgcilvgvll vpltvkcfgk
      301 kqvylagmvl wavgdilnyf wgsnsftfvm fsciaffgta fvnslnwalv pdtvdygewk
      361 tgiraegsvy tgytffrkis aalagflpgi mltqigyvpn iaqsdatlqg lrqlifiwpc
      421 alaiiaaltm gffytlnekr faliieeinq rknkematee ktasvtl