mannose-1-phosphate guanylyltransferase/mannose-6-phosphate

LOCUS       WP_001278239             482 aa            linear   BCT 23-MAY-2024
            isomerase [Escherichia coli].
ACCESSION   WP_001278239
VERSION     WP_001278239.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01479.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..482
                     /product="mannose-1-phosphate
                     guanylyltransferase/mannose-6-phosphate isomerase"
                     /EC_number="2.7.7.13"
                     /EC_number="5.3.1.8"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=54139
     Region          6..480
                     /region_name="GMP_PMI"
                     /note="mannose-1-phosphate
                     guanylyltransferase/mannose-6-phosphate isomerase;
                     TIGR01479"
                     /db_xref="CDD:273648"
     Site            order(11,13,119)
                     /site_type="active"
                     /note="Substrate binding site [active]"
                     /db_xref="CDD:133003"
ORIGIN      
        1 msdapiiavv maggtgsrlw plsrelypkq flqlsgdntl lqttllrlsg lscqkplvit
       61 neqhrfvvae qlreinklng niilepcgrn tapaiaisaf halkrnpqed plllvlaadh
      121 viakesvfcd aiknatpian qgkivtfgii peyaetgygy iergelsvpl qghentgfyy
      181 vnkfvekpnr etaelymtsg nhywnsgifm fkasvyleel rkfrpdiynv ceqvasssyi
      241 dldfirlske qfqdcpaesi dfavmektek cvvcpvdigw sdvgswqslw dislksktgd
      301 vckgdiltyd tknnyiyses alvaaigied mvivqtkdav lvskksdvqh vkkivemlkl
      361 qqrteyishr evfrpwgkfd sidqgerykv kkiivkpgeg lslrmhhhrs ehwivlsgta
      421 kvtlgdktkl vtanesiyip lgaayslenp giiplnliev ssgdylgedd iirqkerykh
      481 ed