phosphomethylpyrimidine synthase ThiC [Escherichia coli].

LOCUS       WP_001276909             631 aa            linear   BCT 16-JUN-2019
ACCESSION   WP_001276909
VERSION     WP_001276909.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF006763.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK09284
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..631
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..631
                     /gene="thiC"
     Protein         1..631
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /EC_number="4.1.99.17"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=70683
     Region          9..626
                     /region_name="PRK09284"
                     /note="thiamine biosynthesis protein ThiC; Provisional"
                     /db_xref="CDD:236451"
ORIGIN      
        1 msatkltrre qraqaqhfid tlegtafpns kriyitgtqp gvrvpmreiq lsptliggsk
       61 eqpqyeenea ipvydtsgpy gdpqiainvq qglaklrqpw idargdteel tvrssdytka
      121 rladdgldel rfsgvltpkr akagrrvtql hyarqgiitp emefiairen mgrerirsev
      181 lrhqhpgmsf garlpenita efvrdevaag raiipaninh pesepmiigr nflvkvnani
      241 gnsavtssie eeveklvwst rwgadtvmdl stgryihetr ewilrnspvp igtvpiyqal
      301 ekvngiaedl tweafrdtll eqaeqgvdyf tihagvllry vpmtakrltg ivsrggsima
      361 kwclshhqen flyqhfreic eicaaydvsl slgdglrpgs iqdandeaqf aelhtlgelt
      421 kiaweydvqv miegpghvpm qmirrnmtee lehcheapfy tlgplttdia pgydhftsgi
      481 gaamigwfgc amlcyvtpke hlglpnkedv kqglitykia ahaadlakgh pgaqirdnam
      541 skarfefrwe dqfnlaldpf tarayhdetl pqesgkvahf csmcgpkfcs mkisqevrdy
      601 aatqtiemgi admsenfrar ggeiylrkee a