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MULTISPECIES: OFA family MFS transporter [Salmonella].


LOCUS       WP_001276365             398 aa            linear   BCT 24-MAR-2023
ACCESSION   WP_001276365
VERSION     WP_001276365.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 398)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 398)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13024068
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..398
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     Protein         1..398
                     /product="OFA family MFS transporter"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=42965
     Region          6..385
                     /region_name="MFS_OFA_like"
                     /note="Oxalate:formate antiporter (OFA) and similar
                     proteins of the Major Facilitator Superfamily of
                     transporters; cd17353"
                     /db_xref="CDD:340911"
     Site            order(17..18,21..22,25,60,111..112,114..116,119,138,
                     141..142,145,220,223..224,227..229,232,258,262,312..313,
                     317,321,337,340..341,344..345,348)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340911"
ORIGIN      
        1 msasinrwgm laahvcinfv lggvyafsyf ktplmaqyhw dpatlalafs inmgiiplpm
       61 iwggrmidng kgkqaivigg ilfslgfils gfvdnlpmlf ltygviaglg sglaftgnln
      121 nilkffpdrr glasgivlag vgvgtllctr laeyfmaqth dvsrallylg ivylvvifiv
      181 qffirsapak dsggikaspl dkdyrhmlkd lrfwllfmil algvfsgmvi ssssaqigmt
      241 qygllsgalv vslvsifnsi grlfwggltd klggyntlvi vylftcvcml lllffngnts
      301 vfyfsalgvg fayagilvif pgltsqnfgm rnqglnygfm yfgfavgavi apyvtsaiak
      361 ytgsyntvfi lttvllligv vltlitkkyv atvlakih