MULTISPECIES: 2-methylcitrate dehydratase [Enterobacteriaceae].

LOCUS       WP_001275859             483 aa            linear   BCT 23-JUN-2024
ACCESSION   WP_001275859
VERSION     WP_001275859.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 483)
  AUTHORS   Brock,M., Maerker,C., Schutz,A., Volker,U. and Buckel,W.
  TITLE     Oxidation of propionate to pyruvate in Escherichia coli.
            Involvement of methylcitrate dehydratase and aconitase
  JOURNAL   Eur J Biochem 269 (24), 6184-6194 (2002)
   PUBMED   12473114
REFERENCE   2  (residues 1 to 483)
  AUTHORS   Blank,L., Green,J. and Guest,J.R.
  TITLE     AcnC of Escherichia coli is a 2-methylcitrate dehydratase (PrpD)
            that can use citrate and isocitrate as substrates
  JOURNAL   Microbiology (Reading) 148 (Pt 1), 133-146 (2002)
   PUBMED   11782506
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02330.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..483
                     /gene="prpD"
     Protein         1..483
                     /product="2-methylcitrate dehydratase"
                     /EC_number="4.2.1.79"
                     /GO_function="GO:0047547 - 2-methylcitrate dehydratase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster
                     binding [Evidence IEA]"
                     /GO_process="GO:0019679 - propionate metabolic process,
                     methylcitrate cycle [Evidence IEA]"
                     /calculated_mol_wt=53821
     Region          1..483
                     /region_name="prpD"
                     /note="bifunctional 2-methylcitrate dehydratase/aconitate
                     hydratase; PRK09425"
                     /db_xref="CDD:181845"
ORIGIN      
        1 msaqinnirp efdreivdiv dyvmnyeiss kvaydtahyc lldtlgcgle aleypackkl
       61 lgpivpgtvv pngvrvpgtq fqldpvqaaf nigamirwld fndtwlaaew ghpsdnlggi
      121 latadwlsrn avasgkaplt mkqvltamik aheiqgcial ensfnrvgld hvllvkvast
      181 avvaemlglt reeilnavsl awvdgqslrt yrhapntgtr kswaagdats ravrlalmak
      241 tgemgypsal tapvwgfydv sfkgesfrfq rpygsyvmen vlfkisfpae fhsqtaveaa
      301 mtlyeqmqaa gktaadiekv tirtheacir iidkkgplnn padrdhciqy mvaipllfgr
      361 ltaadyednv aqdkridalr ekincfedpa ftadyhdpek raianaitle ftdgtrfeev
      421 vveypighar rrqdgipklv dkfkinlarq fptrqqqril evsldrarle qmpvneyldl
      481 yvi