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LOCUS WP_001270592 244 aa linear BCT 01-JAN-2025 ACCESSION WP_001270592 VERSION WP_001270592.1 KEYWORDS RefSeq. SOURCE Salmonella ORGANISM Salmonella Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae. REFERENCE 1 (residues 1 to 244) AUTHORS Leader,D.P. and Milner-White,E.J. TITLE The conserved crown bridge loop at the catalytic centre of enzymes of the haloacid dehalogenase superfamily JOURNAL Curr Res Struct Biol 6, 100105 (2023) PUBMED 37786806 REMARK Publication Status: Online-Only REFERENCE 2 (residues 1 to 244) AUTHORS Yang,L., Lu,Y., Tian,W., Feng,Y., Bai,J. and Zhang,H. TITLE Insights into the functional divergence of the haloacid dehalogenase superfamily from phosphomonoesterase to inorganic pyrophosphatase JOURNAL Arch Biochem Biophys 705, 108896 (2021) PUBMED 33940035 REFERENCE 3 (residues 1 to 244) AUTHORS Burroughs,A.M., Allen,K.N., Dunaway-Mariano,D. and Aravind,L. TITLE Evolutionary genomics of the HAD superfamily: understanding the structural adaptations and catalytic diversity in a superfamily of phosphoesterases and allied enzymes JOURNAL J Mol Biol 361 (5), 1003-1034 (2006) PUBMED 16889794 REFERENCE 4 (residues 1 to 244) AUTHORS Allen,K.N. and Dunaway-Mariano,D. TITLE Phosphoryl group transfer: evolution of a catalytic scaffold JOURNAL Trends Biochem Sci 29 (9), 495-503 (2004) PUBMED 15337123 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: Conserved Domain (CDD) Evidence Accession :: Domain architecture ID 11576297 Evidence Source :: NCBI SPARCLE ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..244 /organism="Salmonella" /db_xref="taxon:590" Protein 1..244 /product="Cof-type HAD-IIB family hydrolase" /EC_number="3.-.-.-" /GO_function="GO:0016787 - hydrolase activity [Evidence IEA]" /calculated_mol_wt=27735 Region 5..235 /region_name="HAD_Pase" /note="phosphatase, similar to Escherichia coli Cof and Thermotoga maritima TM0651; belongs to the haloacid dehalogenase-like superfamily; cd07516" /db_xref="CDD:319818" Site order(9..13,43..44,168,190..192,194..195) /site_type="active" /db_xref="CDD:319818" ORIGIN 1 mryrliafdl dgtllnrnkq ilpesltair qmqdmgcrim lvtgrshrea yayyqtlalt 61 epmiccngsy iyqpaqqqil hplplthlqt ekilarvypl kptiraddki ifqadelssr 121 eniwqisivh rhikqlqnia efiqhelhls ctwswhhqld ilqkgcskgq slaryaqqqh 181 iamrevmafg dndndaemlr laglgvamgn asarakvyad svigrhntpa iadflatlsl 241 sqre