MULTISPECIES: bifunctional aspartate kinase/homoserine

LOCUS       WP_001264707             820 aa            linear   BCT 16-DEC-2020
            dehydrogenase I [Enterobacteriaceae].
ACCESSION   WP_001264707
VERSION     WP_001264707.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 820)
  AUTHORS   Theze,J., Margarita,D., Cohen,G.N., Borne,F. and Patte,J.C.
  TITLE     Mapping of the structural genes of the three aspartokinases and of
            the two homoserine dehydrogenases of Escherichia coli K-12
  JOURNAL   J. Bacteriol. 117 (1), 133-143 (1974)
   PUBMED   4148765
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF006959.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK09436
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..820
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..820
                     /gene="thrA"
     Protein         1..820
                     /product="bifunctional aspartate kinase/homoserine
                     dehydrogenase I"
                     /EC_number="1.1.1.3"
                     /EC_number="2.7.2.4"
                     /GO_function="GO:0004072 - aspartate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_process="GO:0008652 - cellular amino acid biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0009067 - aspartate family amino acid
                     biosynthetic process [Evidence IEA]"
                     /calculated_mol_wt=88990
     Region          1..820
                     /region_name="thrA"
                     /note="bifunctional aspartokinase I/homoserine
                     dehydrogenase I; Provisional; PRK09436"
                     /db_xref="CDD:181856"
ORIGIN      
        1 mrvlkfggts vanaerflrv adilesnarq gqvatvlsap akitnhlvam iektisgqda
       61 lpnisdaeri faelltglaa aqpgfplaql ktfvdqefaq ikhvlhgisl lgqcpdsina
      121 alicrgekms iaimagvlea rghnvtvidp vekllavghy lestvdiaes trriaasrip
      181 adhmvlmagf tagnekgelv vlgrngsdys aavlaaclra dcceiwtdvd gvytcdprqv
      241 pdarllksms yqeamelsyf gakvlhprti tpiaqfqipc likntgnpqa pgtligasrd
      301 edelpvkgis nlnnmamfsv sgpgmkgmvg maarvfaams rarisvvlit qssseysisf
      361 cvpqsdcvra eramqeefyl elkegllepl avterlaiis vvgdgmrtlr gisakffaal
      421 araninivai aqgssersis vvvnnddatt gvrvthqmlf ntdqvievfv igvggvggal
      481 leqlkrqqsw lknkhidlrv cgvanskall tnvhglnlen wqeelaqake pfnlgrlirl
      541 vkeyhllnpv ivdctssqav adqyadflre gfhvvtpnkk antssmdyyh qlryaaeksr
      601 rkflydtnvg aglpvienlq nllnagdelm kfsgilsgsl syifgkldeg msfseattla
      661 remgytepdp rddlsgmdva rkllilaret greleladie iepvlpaefn aegdvaafma
      721 nlsqlddlfa arvakardeg kvlryvgnid edgvcrvkia evdgndplfk vkngenalaf
      781 yshyyqplpl vlrgygagnd vtaagvfadl lrtlswklgv