signal peptide peptidase SppA [Escherichia coli].

LOCUS       WP_001259814             618 aa            linear   BCT 11-DEC-2019
ACCESSION   WP_001259814
VERSION     WP_001259814.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 618)
  AUTHORS   Ichihara,S., Suzuki,T., Suzuki,M. and Mizushima,S.
  TITLE     Molecular cloning and sequencing of the sppA gene and
            characterization of the encoded protease IV, a signal peptide
            peptidase, of Escherichia coli
  JOURNAL   J. Biol. Chem. 261 (20), 9405-9411 (1986)
   PUBMED   3522590
REFERENCE   2  (residues 1 to 618)
  AUTHORS   Ichihara,S., Beppu,N. and Mizushima,S.
  TITLE     Protease IV, a cytoplasmic membrane protein of Escherichia coli,
            has signal peptide peptidase activity
  JOURNAL   J. Biol. Chem. 259 (15), 9853-9857 (1984)
   PUBMED   6378913
REFERENCE   3  (residues 1 to 618)
  AUTHORS   Pacaud,M.
  TITLE     Purification and characterization of two novel proteolytic enzymes
            in membranes of Escherichia coli. Protease IV and protease V
  JOURNAL   J. Biol. Chem. 257 (8), 4333-4339 (1982)
   PUBMED   7040383
REFERENCE   4  (residues 1 to 618)
  AUTHORS   Regnier,P.
  TITLE     The purification of protease IV of E. coli and the demonstration
            that it is an endoproteolytic enzyme
  JOURNAL   Biochem. Biophys. Res. Commun. 99 (4), 1369-1376 (1981)
   PUBMED   7020700
REFERENCE   5  (residues 1 to 618)
  AUTHORS   Regnier,P.
  TITLE     Identification of protease IV of E, coli
  JOURNAL   Biochem. Biophys. Res. Commun. 99 (3), 844-854 (1981)
   PUBMED   7018496
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008195.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10949
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..618
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..618
                     /gene="sppA"
     Protein         1..618
                     /product="signal peptide peptidase SppA"
                     /EC_number="3.4.21.-"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /calculated_mol_wt=67012
     Region          1..618
                     /region_name="PRK10949"
                     /note="signal peptide peptidase SppA"
                     /db_xref="CDD:182860"
ORIGIN      
        1 mrtlwrfiag ffkwtwrlln fvremvlnlf fiflvlvgvg iwmqvsggds ketasrgall
       61 ldisgvivdk pdssqrfskl srqllgassd rlqenslfdi vntirqakdd rnitgivmdl
      121 knfaggdqps mqyigkalke frdsgkpvya vgenysqgqy ylasfankiw lspqgvvdlh
      181 gfatnglyyk slldklkvst hvfrvgtyks avepfirddm spaareadsr wigelwqnyl
      241 ntvaanrqip aqqvfpgaqg llegltktgg dtakyalenk lvdalassae iekaltkefg
      301 wskadknyra isyydyalkt padtgdsigv vfangaimdg eetqgnvggd ttaaqirdar
      361 ldpkvkaivl rvnspggsvt aseviraela aaraagkpvv vsmggmaasg gywistpany
      421 ivanpstltg sigifgvitt vensldsigv htdgvstspl advsitralp peaqqmmqls
      481 iengykrfit lvadarhstp eqidkiaqgh vwtgqdakan glvdslgdfd davakaaela
      541 kakqwhleyy vdeptffdkv mdnmsgsvra mlpdafqaml paplasvast vksesdklaa
      601 fndpqnryaf cltcanvr