dTMP kinase [Escherichia coli].

LOCUS       WP_001256997             213 aa            linear   BCT 03-JUN-2024
ACCESSION   WP_001256997
VERSION     WP_001256997.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 213)
  AUTHORS   Reynes,J.P., Tiraby,M., Baron,M., Drocourt,D. and Tiraby,G.
  TITLE     Escherichia coli thymidylate kinase: molecular cloning, nucleotide
            sequence, and genetic organization of the corresponding tmk locus
  JOURNAL   J Bacteriol 178 (10), 2804-2812 (1996)
   PUBMED   8631667
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00041.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..213
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..213
                     /gene="tmk"
     Protein         1..213
                     /product="dTMP kinase"
                     /EC_number="2.7.4.9"
                     /GO_function="GO:0004798 - thymidylate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=23685
     Region          1..200
                     /region_name="DTMP_kinase"
                     /note="dTMP kinase; TIGR00041"
                     /db_xref="CDD:161676"
     Site            order(17,74,78,99..100,108,153)
                     /site_type="active"
                     /note="TMP-binding site [active]"
                     /db_xref="CDD:238835"
     Site            order(18,149,189)
                     /site_type="other"
                     /note="ATP-binding site [chemical binding]"
                     /db_xref="CDD:238835"
ORIGIN      
        1 mrskyivieg legagkttar nvvvetleql girdmvftre pggtqlaekl rslvldiksv
       61 gdeiitdkae vlmfyaarvq lvetvikpal angtwvigdr hdlstqayqg ggrgidqhml
      121 atlrdavlgd frpdltlyld vtpevglkra rargeldrie qesfdffnrt rarylelaaq
      181 dksihtidat qpleavmdai rttvtrwvke lda