MULTISPECIES: S49 family peptidase [Shigella].

LOCUS       WP_001254019             501 aa            linear   BCT 23-JUL-2024
ACCESSION   WP_001254019
VERSION     WP_001254019.1
KEYWORDS    RefSeq.
SOURCE      Shigella
  ORGANISM  Shigella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 501)
  AUTHORS   Rawlings,N.D. and Barrett,A.J.
  TITLE     Families of serine peptidases
  JOURNAL   Methods Enzymol 244, 19-61 (1994)
   PUBMED   7845208
REFERENCE   2  (residues 1 to 501)
  AUTHORS   Rawlings,N.D. and Barrett,A.J.
  TITLE     Evolutionary families of peptidases
  JOURNAL   Biochem J 290 (Pt 1) (Pt 1), 205-218 (1993)
   PUBMED   8439290
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10161638
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..501
                     /organism="Shigella"
                     /db_xref="taxon:620"
     Protein         1..501
                     /product="S49 family peptidase"
                     /EC_number="3.4.21.-"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /calculated_mol_wt=52434
     Region          77..290
                     /region_name="S49_Sppa_36K_type"
                     /note="Signal peptide peptidase A (SppA) 36K type, a
                     serine protease, has catalytic Ser-Lys dyad; cd07022"
                     /db_xref="CDD:132933"
     Site            order(84,125,162,177,179,187..190,239,262..264,266,269)
                     /site_type="other"
                     /note="tandem repeat interface [polypeptide binding]"
                     /db_xref="CDD:132933"
     Site            order(104,111,137,203,205..209,237,241)
                     /site_type="other"
                     /note="oligomer interface [polypeptide binding]"
                     /db_xref="CDD:132933"
     Site            162
                     /site_type="active"
                     /note="active site residues [active]"
                     /db_xref="CDD:132933"
ORIGIN      
        1 mrrnlshiia aafnepllle payarvffca lgremgaasl svpqqqvqld apgmlaetde
       61 ymaggkrpar vyrvvngiav lpvtgtlvhr lggmrpfsgm tgydgivacl qqamadtqvr
      121 gvlldidssg gqatgafdca dmiyrlrqlk pvwalcndta csaamllasa csrrlvtqts
      181 rigsigvmmg hvsyaghlaq agvditliya gshkvdgnqf eslpakvrqd mqqridaarr
      241 mfaekvamyt glsvdavmgt eaavfegqsg ieaeladeli nasdaisvma atlnthdtgg
      301 tmpqltatea aaqenqrvmg iltcqeakgr eqlatmlagq qgmsveqara ilavaapqqs
      361 gvsaqseadr imaceeakgr eqlaatlaam pemtvekarp ilaaspqana gpslrdqima
      421 ldeakgaeaq aeklaacpgm tvenaravla aasgraepvs asttamfehf manhspaavq
      481 ggvpqtsadg dadvkmlmam p