S49 family peptidase [Escherichia coli].

LOCUS       WP_001254002             501 aa            linear   BCT 23-JUL-2024
ACCESSION   WP_001254002
VERSION     WP_001254002.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 501)
  AUTHORS   Rawlings,N.D. and Barrett,A.J.
  TITLE     Families of serine peptidases
  JOURNAL   Methods Enzymol 244, 19-61 (1994)
   PUBMED   7845208
REFERENCE   2  (residues 1 to 501)
  AUTHORS   Rawlings,N.D. and Barrett,A.J.
  TITLE     Evolutionary families of peptidases
  JOURNAL   Biochem J 290 (Pt 1) (Pt 1), 205-218 (1993)
   PUBMED   8439290
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10161638
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..501
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..501
                     /product="S49 family peptidase"
                     /EC_number="3.4.21.-"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /calculated_mol_wt=52196
     Region          77..290
                     /region_name="S49_Sppa_36K_type"
                     /note="Signal peptide peptidase A (SppA) 36K type, a
                     serine protease, has catalytic Ser-Lys dyad; cd07022"
                     /db_xref="CDD:132933"
     Site            order(84,125,162,177,179,187..190,239,262..264,266,269)
                     /site_type="other"
                     /note="tandem repeat interface [polypeptide binding]"
                     /db_xref="CDD:132933"
     Site            order(104,111,137,203,205..209,237,241)
                     /site_type="other"
                     /note="oligomer interface [polypeptide binding]"
                     /db_xref="CDD:132933"
     Site            162
                     /site_type="active"
                     /note="active site residues [active]"
                     /db_xref="CDD:132933"
ORIGIN      
        1 mrrnlshiia aafnepllle payarvffca lgremgaasl svpqqqvqld apgmlaetde
       61 ymaggkrpar vyrvvngiav lpvtgtlvhr lggmrpfsgm tgydgivacl qqamadsqvr
      121 gvlldidspg gqaagafdca dmiyrlrqqk pvwalcndta csaamllasa csrrlvtqts
      181 rigsigvmms hvsyaghlaq agvditliys gahkvdgnqf ealpaevrqn mqqridaarr
      241 mfaekvamft glsvdavtgt eaavfegqsg idagladelv nasdaisvma talnsnvrgg
      301 tmpqltatea aaqenqrvmg iltcqeakgr eqlatmlagq qgmsveqara ilaaaapqqp
      361 vastqseadr imaceeangr eqlaatlaam pemtvekarp ilaaspqada gpslrdqima
      421 ldeakgaeaq aeqlaacpgm tvesaravla agsgkaepvs asttalferi manhspaavq
      481 ggvpqtsadg dadvkmlmam p