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LOCUS WP_001253818 450 aa linear BCT 17-OCT-2022 [Salmonella]. ACCESSION WP_001253818 VERSION WP_001253818.1 KEYWORDS RefSeq. SOURCE Salmonella ORGANISM Salmonella Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae. REFERENCE 1 (residues 1 to 450) AUTHORS Reboul,A., Lemaitre,N., Titecat,M., Merchez,M., Deloison,G., Ricard,I., Pradel,E., Marceau,M. and Sebbane,F. TITLE Yersinia pestis requires the 2-component regulatory system OmpR-EnvZ to resist innate immunity during the early and late stages of plague JOURNAL J Infect Dis 210 (9), 1367-1375 (2014) PUBMED 24813471 REFERENCE 2 (residues 1 to 450) AUTHORS Tomomori,C., Tanaka,T., Dutta,R., Park,H., Saha,S.K., Zhu,Y., Ishima,R., Liu,D., Tong,K.I., Kurokawa,H., Qian,H., Inouye,M. and Ikura,M. TITLE Solution structure of the homodimeric core domain of Escherichia coli histidine kinase EnvZ JOURNAL Nat Struct Biol 6 (8), 729-734 (1999) PUBMED 10426948 REFERENCE 3 (residues 1 to 450) AUTHORS Tanaka,T., Saha,S.K., Tomomori,C., Ishima,R., Liu,D., Tong,K.I., Park,H., Dutta,R., Qin,L., Swindells,M.B., Yamazaki,T., Ono,A.M., Kainosho,M., Inouye,M. and Ikura,M. TITLE NMR structure of the histidine kinase domain of the E. coli osmosensor EnvZ JOURNAL Nature 396 (6706), 88-92 (1998) PUBMED 9817206 REFERENCE 4 (residues 1 to 450) AUTHORS Yaku,H. and Mizuno,T. TITLE The membrane-located osmosensory kinase, EnvZ, that contains a leucine zipper-like motif functions as a dimer in Escherichia coli JOURNAL FEBS Lett 417 (3), 409-413 (1997) PUBMED 9409762 REFERENCE 5 (residues 1 to 450) AUTHORS Forst,S., Comeau,D., Norioka,S. and Inouye,M. TITLE Localization and membrane topology of EnvZ, a protein involved in osmoregulation of OmpF and OmpC in Escherichia coli JOURNAL J Biol Chem 262 (34), 16433-16438 (1987) PUBMED 2824492 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: NF007004.0 Evidence Source :: NCBI Protein Cluster (PRK) Source Identifier :: PRK09467 ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..450 /organism="Salmonella" /db_xref="taxon:590" gene 1..450 /gene="envZ" Protein 1..450 /product="two-component system sensor histidine kinase EnvZ" /EC_number="2.7.13.3" /GO_component="GO:0016020 - membrane [Evidence IEA]" /GO_function="GO:0000155 - phosphorelay sensor kinase activity [Evidence IEA]" /GO_process="GO:0007165 - signal transduction [Evidence IEA]" /GO_process="GO:0016310 - phosphorylation [Evidence IEA]" /calculated_mol_wt=50243 Region 4..439 /region_name="envZ" /note="osmolarity sensor protein; Provisional; PRK09467" /db_xref="CDD:236531" ORIGIN 1 mrrmrfsprs sfartllliv tllfvslvtt ylvvlnfail pslqqfnkvl ayevrmlmtd 61 klqledgtql vvppafrrei yrelgislyt neaaeeaglr waqhyeflsh qmaqqlggpt 121 evrvevnkss pvvwlktwls pniwvrvplt eihqgdfspl frytlaimll aiggawlfir 181 iqnrplvdle haalqvgkgi ippplreyga sevrsvtraf nhmaagvkql addrtllmag 241 vshdlrtplt rirlatemmg eedgylaesi nkdieecnai ieqfidylrt gqempmemad 301 lnsvlgevia aesgyerein talqagsiqv kmhplsikra vanmvvnaar ygngwikvss 361 gteshrawfq veddgpgikp eqrkhlfqpf vrgdsarsts gtglglaivq riidnhngml 421 eigtserggl sirawlpvpv arvqgttkea