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MULTISPECIES: fosmidomycin MFS transporter [Shigella].


LOCUS       WP_001251629             406 aa            linear   BCT 17-NOV-2023
ACCESSION   WP_001251629
VERSION     WP_001251629.1
KEYWORDS    RefSeq.
SOURCE      Shigella
  ORGANISM  Shigella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 406)
  AUTHORS   Fujisaki,S., Ohnuma,S., Horiuchi,T., Takahashi,I., Tsukui,S.,
            Nishimura,Y., Nishino,T., Kitabatake,M. and Inokuchi,H.
  TITLE     Cloning of a gene from Escherichia coli that confers resistance to
            fosmidomycin as a consequence of amplification
  JOURNAL   Gene 175 (1-2), 83-87 (1996)
   PUBMED   8917080
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011163
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Shigella"
                     /db_xref="taxon:620"
     gene            1..406
                     /gene="fsr"
     Protein         1..406
                     /product="fosmidomycin MFS transporter"
                     /calculated_mol_wt=43248
     Region          30..398
                     /region_name="MFS_FsR"
                     /note="Fosmidomycin resistance protein of the Major
                     Facilitator Superfamily of transporters; cd17478"
                     /db_xref="CDD:341031"
     Site            order(37..38,41..42,45,77,127..128,130..132,135,154,
                     157..158,161,236,239..240,243..245,248,276,280,328..329,
                     333,337,352,355..356,359..360,363)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:341031"
ORIGIN      
        1 mamseqtqpv agaaasttka rtsfgilgai slshllndmi qslilaiypl lqsefsltfm
       61 qigmitltfq lassllqpvv gywtdkypmp wslpigmcft lsglvllala gsfgavllaa
      121 alvgtgssvf hpessrvarm asggrhglaq sifqvggnfg sslgpllaav iiapygkgnv
      181 awfvlaalla ivvlaqisrw ysaqhrmnkg kpkatiinpl prnkvvlavs illilifsky
      241 fymasissyy tfylmqkfgl siqnaqlhlf aflfavaagt viggpvgdki grkyviwgsi
      301 lgvapftlil pyarlhwtgv ltviigfila safsailvya qellpgrigm vsglffgfaf
      361 gmgglgaavl gliadhtsie lvykicaflp llgmltiflp dnrhkd