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MULTISPECIES: MFS transporter [Salmonella].


LOCUS       WP_001251593             406 aa            linear   BCT 25-MAR-2023
ACCESSION   WP_001251593
VERSION     WP_001251593.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 406)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 406)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13024721
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     Protein         1..406
                     /product="MFS transporter"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=42926
     Region          30..398
                     /region_name="MFS_FsR"
                     /note="Fosmidomycin resistance protein of the Major
                     Facilitator Superfamily of transporters; cd17478"
                     /db_xref="CDD:341031"
     Site            order(37..38,41..42,45,77,127..128,130..132,135,154,
                     157..158,161,236,239..240,243..245,248,276,280,328..329,
                     333,337,352,355..356,359..360,363)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:341031"
ORIGIN      
        1 mamseptqpl agapaaaaka rtsfgilgai slshllndmi qslilaiypl lqaefsltfv
       61 qiglitltfq lassllqpvv gywtdkypmp wslpvgmcft lsglvllama gsfggvllaa
      121 alvgtgssvf hpessrvarm asggrhglaq sifqvggnfg sslgpllaav iiapygkgnv
      181 awfvlaalla ivvlaqisrw yaaqhriakg kpkaiianpl prnkvvlavs vllllifsky
      241 fymasissyy tfylmqkfgl siqnaqlhlf aflfavaagt viggpvgdki grkyviwgsi
      301 lgvapftlvl pyatlywtgi ltviigfila safsailvya qellpgrigm vsglffgfaf
      361 gmgglgaavl gliadhtsiy lvykicaflp llgiltiflp dnrhka