MULTISPECIES: imidazolonepropionase [Salmonella].

LOCUS       WP_001249472             407 aa            linear   BCT 02-JUN-2024
ACCESSION   WP_001249472
VERSION     WP_001249472.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 407)
  AUTHORS   Tyagi,R., Kumaran,D., Burley,S.K. and Swaminathan,S.
  TITLE     X-ray structure of imidazolonepropionase from Agrobacterium
            tumefaciens at 1.87 A resolution
  JOURNAL   Proteins 69 (3), 652-658 (2007)
   PUBMED   17640072
REFERENCE   2  (residues 1 to 407)
  AUTHORS   Yu,Y., Liang,Y.H., Brostromer,E., Quan,J.M., Panjikar,S., Dong,Y.H.
            and Su,X.D.
  TITLE     A catalytic mechanism revealed by the crystal structures of the
            imidazolonepropionase from Bacillus subtilis
  JOURNAL   J Biol Chem 281 (48), 36929-36936 (2006)
   PUBMED   16990261
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01224.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..407
                     /gene="hutI"
     Protein         1..407
                     /product="imidazolonepropionase"
                     /EC_number="3.5.2.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0016812 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in cyclic amides
                     [Evidence IEA]"
                     /GO_function="GO:0050480 - imidazolonepropionase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019556 - histidine catabolic process to
                     glutamate and formamide [Evidence IEA]"
                     /calculated_mol_wt=44498
     Region          35..404
                     /region_name="Imidazolone-5PH"
                     /note="Imidazolonepropionase/imidazolone-5-propionate
                     hydrolase (Imidazolone-5PH) catalyzes the third step in
                     the histidine degradation pathway, the hydrolysis of
                     (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to
                     N-formimidoyl-L-glutamate. In bacteria; cd01296"
                     /db_xref="CDD:238621"
     Site            order(74,76,244,247,267,319)
                     /site_type="active"
                     /db_xref="CDD:238621"
ORIGIN      
        1 mrqllpgdtv wrnirlatmd pqqqalyglv dnqalivreg hicdivpetq lpvsgdnihd
       61 mqgrlvtpgl idchthlvfa gnraaeweqr lngasyqhis aqggginatv satracaeet
      121 lyllarermm rlasegvtll eiksgyglel ateekllrva aklaaenaid isptllaaha
      181 tpaeyrddpd gyitlvcetm ipqlwqkglf davdlfcesv gfnvaqserv lqtakalgip
      241 vkghveqlsl lggaqlvsry qglsadhiey ldevgvaamr dggtvgvllp gafyflretq
      301 rppvellrry qvpvavasdf npgtspfcsl hlamnmacvq fgltpeeawa gvtrhaaral
      361 grqathgqir agyradfvvw daeqpveivy epgrnplyqr vyrgkis