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MULTISPECIES: DNA-binding transcriptional regulator IdnR


LOCUS       WP_001244065             332 aa            linear   BCT 13-JAN-2025
            [Salmonella].
ACCESSION   WP_001244065
VERSION     WP_001244065.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 332)
  AUTHORS   Bausch,C., Peekhaus,N., Utz,C., Blais,T., Murray,E., Lowary,T. and
            Conway,T.
  TITLE     Sequence analysis of the GntII (subsidiary) system for gluconate
            metabolism reveals a novel pathway for L-idonic acid catabolism in
            Escherichia coli
  JOURNAL   J Bacteriol 180 (14), 3704-3710 (1998)
   PUBMED   9658018
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF047913.1
            Evidence Source    :: NCBIFAM
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..332
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..332
                     /gene="idnR"
                     /gene_synonym="gntH; yjgS"
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
     Protein         1..332
                     /product="DNA-binding transcriptional regulator IdnR"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0019521 - D-gluconate metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=37524
     Region          6..75
                     /region_name="HTH_LACI"
                     /note="helix_turn _helix lactose operon repressor;
                     smart00354"
                     /db_xref="CDD:197675"
     Site            order(9,17..21,23..24,27,32..33,36,49,52,55..56,58)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     Site            49..58
                     /site_type="active"
                     /note="domain linker motif [active]"
                     /db_xref="CDD:143331"
     Region          65..331
                     /region_name="PBP1_GntR"
                     /note="ligand-binding domain of DNA transcription
                     repressor GntR specific for gluconate, a member of the
                     LacI-GalR family of bacterial transcription regulators;
                     cd01575"
                     /db_xref="CDD:380489"
     Site            order(73,79,82,86,95..98,111,114..115,117..118,223,225,
                     228,257)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:380489"
     Site            order(77..78,81,126,149,162,198,222,276,293)
                     /site_type="other"
                     /note="putative ligand binding site [chemical binding]"
                     /db_xref="CDD:380489"
ORIGIN      
        1 mrnhrislqd iatlagvtkm tvsryirspk kvaretgeri aqimeeinyi pnrapamlln
       61 aqsytlgvli psfqnqlfad ilagiesvts ghnyqtlian ynynrdseee svinllsyni
      121 dgiilsekyh tlrtvkflrs atlpivelmd iqgdrldmev gfdnrqaafd mvstmldkrq
      181 rrkilylgsk ddirdeqryh gycdamtrrg laplrinpra issihlgiql mrdaltahpd
      241 vdgvfctndd iamgallwcr erqlavpeqi siagfhglem grqmipslas vitprfeigr
      301 raaqmllnki knndlnhnti dlgyqiyhgs tl