DNA topoisomerase III [Escherichia coli].

LOCUS       WP_001235841             653 aa            linear   BCT 24-FEB-2020
ACCESSION   WP_001235841
VERSION     WP_001235841.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 653)
  AUTHORS   Changela,A., DiGate,R.J. and Mondragon,A.
  TITLE     Structural studies of E. coli topoisomerase III-DNA complexes
            reveal a novel type IA topoisomerase-DNA conformational
            intermediate
  JOURNAL   J. Mol. Biol. 368 (1), 105-118 (2007)
   PUBMED   17331537
REFERENCE   2  (residues 1 to 653)
  AUTHORS   Changela,A., DiGate,R.J. and Mondragon,A.
  TITLE     Crystal structure of a complex of a type IA DNA topoisomerase with
            a single-stranded DNA molecule
  JOURNAL   Nature 411 (6841), 1077-1081 (2001)
   PUBMED   11429611
REFERENCE   3  (residues 1 to 653)
  AUTHORS   Mondragon,A. and DiGate,R.
  TITLE     The structure of Escherichia coli DNA topoisomerase III
  JOURNAL   Structure 7 (11), 1373-1383 (1999)
   PUBMED   10574789
REFERENCE   4  (residues 1 to 653)
  AUTHORS   DiGate,R.J. and Marians,K.J.
  TITLE     Molecular cloning and DNA sequence analysis of Escherichia coli
            topB, the gene encoding topoisomerase III
  JOURNAL   J. Biol. Chem. 264 (30), 17924-17930 (1989)
   PUBMED   2553698
REFERENCE   5  (residues 1 to 653)
  AUTHORS   Srivenugopal,K.S., Lockshon,D. and Morris,D.R.
  TITLE     Escherichia coli DNA topoisomerase III: purification and
            characterization of a new type I enzyme
  JOURNAL   Biochemistry 23 (9), 1899-1906 (1984)
   PUBMED   6326814
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR006644
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..653
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..653
                     /gene="topB"
     Protein         1..653
                     /product="DNA topoisomerase III"
                     /EC_number="5.6.2.1"
                     /calculated_mol_wt=73102
     Region          1..642
                     /region_name="PRK07726"
                     /note="DNA topoisomerase 3"
                     /db_xref="CDD:236078"
ORIGIN      
        1 mrlfiaekps laraiadvlp kphrkgdgfi ecgngqvvtw cighlleqaq pdaydsryar
       61 wnladlpivp ekwqlqprps vtkqlnvikr ylheaseivh agdpdregql lvdevldylq
      121 lapekrqqvq rclindlnpq averaidrlr snsefvplcv salararadw lyginmtray
      181 tilgrnagyq gvlsvgrvqt pvlglvvrrd eeienfvakd ffevkahivt paderftaiw
      241 qpseacepyq deegrllhrp laehvvnris gqpaivtsyn dkresesapl pfslsalqie
      301 aakrfglsaq nvldicqkly ethklitypr sdcrylpeeh fagrhavmna isvhapdllp
      361 qpvvdpdirn rcwddkkvda hhaiiptars sainltenea kvynlisrqy lmqfcpdavf
      421 rkcvieldia kgkfvakarf laeagwrtll gskerdeend gtplpvvakg dellcekgev
      481 verqtqpprh ftdatllsam tgiarfvqdk dlkkilratd glgteatrag iiellfkrgf
      541 likkgryihs tdagkalfhs lpematrpdm tahwesvltq isekqcryqd fmqplvgtly
      601 qlidqakrtp vrqfrgivap gsggsadkkk aaprkrsakk sppadeagsg aia