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MULTISPECIES: DNA polymerase IV [Salmonella].


LOCUS       WP_001226198             351 aa            linear   BCT 11-DEC-2019
ACCESSION   WP_001226198
VERSION     WP_001226198.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 351)
  AUTHORS   Rechkoblit,O., Malinina,L., Cheng,Y., Kuryavyi,V., Broyde,S.,
            Geacintov,N.E. and Patel,D.J.
  TITLE     Stepwise translocation of Dpo4 polymerase during error-free bypass
            of an oxoG lesion
  JOURNAL   PLoS Biol. 4 (1), e11 (2006)
   PUBMED   16379496
REFERENCE   2  (residues 1 to 351)
  AUTHORS   Courcelle,C.T., Belle,J.J. and Courcelle,J.
  TITLE     Nucleotide excision repair or polymerase V-mediated lesion bypass
            can act to restore UV-arrested replication forks in Escherichia
            coli
  JOURNAL   J. Bacteriol. 187 (20), 6953-6961 (2005)
   PUBMED   16199565
REFERENCE   3  (residues 1 to 351)
  AUTHORS   Kuban,W., Banach-Orlowska,M., Bialoskorska,M., Lipowska,A.,
            Schaaper,R.M., Jonczyk,P. and Fijalkowska,I.J.
  TITLE     Mutator phenotype resulting from DNA polymerase IV overproduction
            in Escherichia coli: preferential mutagenesis on the lagging strand
  JOURNAL   J. Bacteriol. 187 (19), 6862-6866 (2005)
   PUBMED   16166552
REFERENCE   4  (residues 1 to 351)
  AUTHORS   Vaisman,A., Ling,H., Woodgate,R. and Yang,W.
  TITLE     Fidelity of Dpo4: effect of metal ions, nucleotide selection and
            pyrophosphorolysis
  JOURNAL   EMBO J. 24 (17), 2957-2967 (2005)
   PUBMED   16107880
REFERENCE   5  (residues 1 to 351)
  AUTHORS   Layton,J.C. and Foster,P.L.
  TITLE     Error-prone DNA polymerase IV is regulated by the heat shock
            chaperone GroE in Escherichia coli
  JOURNAL   J. Bacteriol. 187 (2), 449-457 (2005)
   PUBMED   15629916
REFERENCE   6  (residues 1 to 351)
  AUTHORS   Fujii,S., Gasser,V. and Fuchs,R.P.
  TITLE     The biochemical requirements of DNA polymerase V-mediated
            translesion synthesis revisited
  JOURNAL   J. Mol. Biol. 341 (2), 405-417 (2004)
   PUBMED   15276832
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF002677.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK02406
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..351
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..351
                     /gene="dinB"
     Protein         1..351
                     /product="DNA polymerase IV"
                     /EC_number="2.7.7.7"
                     /GO_function="GO:0003684 - damaged DNA binding [Evidence
                     IEA]"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /calculated_mol_wt=39527
     Region          9..351
                     /region_name="PRK02406"
                     /note="DNA polymerase IV; Validated"
                     /db_xref="CDD:235035"
ORIGIN      
        1 mrkiihvdmd cffaavemrd npalrdipia iggsrerrgv istanyparq fgvrsampta
       61 malklcphlt llpgrfdayk easrhvrdif srytsliepl sldeawldvt dsphcygsat
      121 liareirqti fnelqltasa gvapvkflak iasdlnkpng qyvitpadvp dflktlplak
      181 ipgvgkvsaa klenmglrtc gdiqqcdlam llkrfgkfgr vlwersqgid erdvnserlr
      241 ksvgvertla edihewsdce aiiehlypel errlaivkpd lliarqgvkl kfndfqqttq
      301 ehvwpqlnke dlittarktw derrgergvr lvglhvtlld pqlerqlvlg l