Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: exonuclease subunit SbcD [Enterobacteriaceae].


LOCUS       WP_001221319             400 aa            linear   BCT 29-MAY-2023
ACCESSION   WP_001221319
VERSION     WP_001221319.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 400)
  AUTHORS   Connelly,J.C., Kirkham,L.A. and Leach,D.R.
  TITLE     The SbcCD nuclease of Escherichia coli is a structural maintenance
            of chromosomes (SMC) family protein that cleaves hairpin DNA
  JOURNAL   Proc Natl Acad Sci U S A 95 (14), 7969-7974 (1998)
   PUBMED   9653124
REFERENCE   2  (residues 1 to 400)
  AUTHORS   Gibson,F.P., Leach,D.R. and Lloyd,R.G.
  TITLE     Identification of sbcD mutations as cosuppressors of recBC that
            allow propagation of DNA palindromes in Escherichia coli K-12
  JOURNAL   J Bacteriol 174 (4), 1222-1228 (1992)
   PUBMED   1531222
REFERENCE   3  (residues 1 to 400)
  AUTHORS   Leach,D.R., Lloyd,R.G. and Coulson,A.F.
  TITLE     The SbcCD protein of Escherichia coli is related to two putative
            nucleases in the UvrA superfamily of nucleotide-binding proteins
  JOURNAL   Genetica 87 (2), 95-100 (1992)
   PUBMED   1490631
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008206.2
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10966
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..400
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..400
                     /gene="sbcD"
     Protein         1..400
                     /product="exonuclease subunit SbcD"
                     /EC_number="3.1.11.-"
                     /GO_function="GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence
                     IEA]"
                     /calculated_mol_wt=44583
     Region          1..400
                     /region_name="PRK10966"
                     /note="exonuclease subunit SbcD; Provisional"
                     /db_xref="CDD:182871"
ORIGIN      
        1 mrilhtsdwh lgqnfysksr eaehqafldw lletaqthqv daiivagdvf dtgsppsyar
       61 tlynrfvvnl qqtgchlvvl agnhdsvatl nesrdimafl nttvvasagh apqilprrdg
      121 tpgavlcpip flrprdiits qaglngiekq qhllaaitdy yqqhyadack lrgdqplpii
      181 atghlttvga sksdavrdiy igtldafpaq nfppadyial ghihraqiig gmehvrycgs
      241 piplsfdecg kskyvhlvtf sngklesven lnvpvtqpma vlkgdlasit aqleqwrdvs
      301 qeppvwldie ittdeylhdi qrkiqaltes lpvevllvrr sreqrervla sqqretlsel
      361 sveevfnrrl aleeldesqq qrlqhlfttt lhtlagehea