Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: purine nucleoside transporter PunC [Escherichia].


LOCUS       WP_001182346             403 aa            linear   BCT 19-FEB-2024
ACCESSION   WP_001182346
VERSION     WP_001182346.1
KEYWORDS    RefSeq.
SOURCE      Escherichia
  ORGANISM  Escherichia
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 403)
  AUTHORS   Rodionova,I.A., Gao,Y., Sastry,A., Hefner,Y., Lim,H.G.,
            Rodionov,D.A., Saier,M.H. Jr. and Palsson,B.O.
  TITLE     Identification of a transcription factor, PunR, that regulates the
            purine and purine nucleoside transporter punC in E. coli
  JOURNAL   Commun Biol 4 (1), 991 (2021)
   PUBMED   34413462
  REMARK    Publication Status: Online-Only
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008270.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11043
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Escherichia"
                     /db_xref="taxon:561"
     gene            1..403
                     /gene="punC"
                     /GO_component="GO:0016021 - integral component of membrane
                     [Evidence IEA]"
                     /GO_function="GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:1990961 - xenobiotic detoxification by
                     transmembrane export across the plasma membrane [Evidence
                     IEA]"
     Protein         1..403
                     /product="purine nucleoside transporter PunC"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:1990961 - xenobiotic detoxification by
                     transmembrane export across the plasma membrane [Evidence
                     IEA]"
                     /calculated_mol_wt=43297
     Region          1..403
                     /region_name="PRK11043"
                     /note="Bcr/CflA family multidrug efflux MFS transporter"
                     /db_xref="CDD:182924"
ORIGIN      
        1 mqpgkrflvw laglsvlgfl atdmylpafa aiqadlqtpa savsaslslf lagfaaaqll
       61 wgplsdrygr kpvlliglti falgslgmlw venaamllvl rfvqavgvca aaviwqalvt
      121 dyypsqkvnr ifatimplvg lspalapllg swllvhfswq aifatlfait vvlilpifwl
      181 kpttkarnns qdgltftdll rsktyrgnvl iyaacsasff awltgspfil semgyspavi
      241 glsyvpqtia fliggygcra alqkwqgkql lpwllvlfav sviatwaagf ishvslveil
      301 ipfcvmaian gaiypivvaq alrpfphatg raaalqntlq lglcflaslv vswlisistp
      361 lltttsvmls tvvlvalgym mqrceevgcq nhgnaevahs esh