MULTISPECIES: alpha-keto acid decarboxylase family protein

LOCUS       WP_001180855             550 aa            linear   BCT 01-JAN-2025
            [Salmonella].
ACCESSION   WP_001180855
VERSION     WP_001180855.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 550)
  AUTHORS   Pohl,M., Lingen,B. and Muller,M.
  TITLE     Thiamin-diphosphate-dependent enzymes: new aspects of asymmetric
            C-C bond formation
  JOURNAL   Chemistry 8 (23), 5288-5295 (2002)
   PUBMED   12432496
REFERENCE   2  (residues 1 to 550)
  AUTHORS   Hawkins,C.F., Borges,A. and Perham,R.N.
  TITLE     A common structural motif in thiamin pyrophosphate-binding enzymes
  JOURNAL   FEBS Lett 255 (1), 77-82 (1989)
   PUBMED   2792374
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11467699
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..550
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     Protein         1..550
                     /product="alpha-keto acid decarboxylase family protein"
                     /EC_number="4.1.1.-"
                     /GO_function="GO:0016831 - carboxy-lyase activity
                     [Evidence IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /calculated_mol_wt=59661
     Region          1..543
                     /region_name="PDC1"
                     /note="TPP-dependent 2-oxoacid decarboxylase, includes
                     indolepyruvate decarboxylase [Carbohydrate transport and
                     metabolism, Coenzyme transport and metabolism, General
                     function prediction only]; COG3961"
                     /db_xref="CDD:443161"
ORIGIN      
        1 mqnpytvady lldrlagcgi ghlfgvpgdy nlqfldhvid hptlrwvgca nelnaayaad
       61 gyarmsgaga llttfgvgel saingiagsy aeyvpvlhiv gapcsaaqqr gelmhhtlgd
      121 gdfrhfyrms qaisaasail deqnacfeid rvlgemlaar rpgyimlpad vakktaippt
      181 qalalpvhea qsgvetafry harqclmnsr rialladfla grfglrpllq rwmaetpiah
      241 atllmgkglf deqhpnfvgt ysagasskev rqaiedadrv icvgtrfvdt ltagftqqlp
      301 aertleiqpy asrigetwfn lpmaqavstl relclecafa ppptrsagqp vridkgeltq
      361 esfwqtlqqy lkpgdiilvd qgtaafgaaa lslpdgaevv lqplwgsigy slpaafgaqt
      421 acpdrrvili igdgaaqlti qemgsmlrdg qapvilllnn dgytveraih gaaqryndia
      481 swnwtqippa lnaaqqaecw rvtqaiqlae vlerlarpqr lsfievmlpk adlpellrtv
      541 tralearngg