ShlB/FhaC/HecB family hemolysin secretion/activation protein

LOCUS       WP_001177016             539 aa            linear   BCT 01-JAN-2025
            [Escherichia coli].
ACCESSION   WP_001177016
VERSION     WP_001177016.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 539)
  AUTHORS   Aoki,S.K., Diner,E.J., de Roodenbeke,C.T., Burgess,B.R.,
            Poole,S.J., Braaten,B.A., Jones,A.M., Webb,J.S., Hayes,C.S.,
            Cotter,P.A. and Low,D.A.
  TITLE     A widespread family of polymorphic contact-dependent toxin delivery
            systems in bacteria
  JOURNAL   Nature 468 (7322), 439-442 (2010)
   PUBMED   21085179
REFERENCE   2  (residues 1 to 539)
  AUTHORS   Zeth,K.
  TITLE     Structure and evolution of mitochondrial outer membrane proteins of
            beta-barrel topology
  JOURNAL   Biochim Biophys Acta 1797 (6-7), 1292-1299 (2010)
   PUBMED   20450883
REFERENCE   3  (residues 1 to 539)
  AUTHORS   Hertle,R.
  TITLE     The family of Serratia type pore forming toxins
  JOURNAL   Curr Protein Pept Sci 6 (4), 313-325 (2005)
   PUBMED   16101433
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11458196
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..539
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..539
                     /product="ShlB/FhaC/HecB family hemolysin
                     secretion/activation protein"
                     /GO_component="GO:0046930 - pore complex [Evidence IEA]"
                     /GO_function="GO:0015288 - porin activity [Evidence IEA]"
                     /GO_process="GO:0006811 - monoatomic ion transport
                     [Evidence IEA]"
                     /GO_process="GO:0015031 - protein transport [Evidence
                     IEA]"
                     /calculated_mol_wt=60827
     Region          9..538
                     /region_name="FhaC"
                     /note="Hemolysin activation/secretion protein
                     [Intracellular trafficking, secretion, and vesicular
                     transport]; COG2831"
                     /db_xref="CDD:442079"
ORIGIN      
        1 mqlrfnfgll lilccfqvaa kdsldnlikq qknadestlr ahklekkdvy snaqrnaftl
       61 gdlpqekncf iinrieledn flggqlisev qkaiagrcvg sagvqkiaaa lqdyyinagy
      121 ittrisipsq diskgklrfq vnagkiekti vegndisewm lpfqrndiln irdieqglen
      181 lqrvpdvdvk iniepgtrdg ysivhidthr gknwsvrasy nnwgdeetgr yqttsvgylf
      241 npakmgdlfy lagtrsttgq yenvssyysi pvgyweygff ysksksqqvi plsyisldyv
      301 giseylsaka thtvyrdktk kfagsaelir rksnytlnge eltlqardmg niklglnykq
      361 qlpgafwdst lswqrfltwf ggektpdmqy gdvspvsnif nfegnytrqi engyyntaff
      421 aqyapreltl qdkitvgdrw sirgfensvg lsgndgfyik ntlafplpgm kanyyagldf
      481 gqvyqdasyg deslvgsavg idgniksley nfsvstplky patldidrvn vnfnfsyqm