MULTISPECIES: NADP-dependent succinate-semialdehyde dehydrogenase

LOCUS       WP_001176529             482 aa            linear   BCT 31-MAY-2019
            [Salmonella].
ACCESSION   WP_001176529
VERSION     WP_001176529.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008415.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11241
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..482
                     /gene="gabD"
     Protein         1..482
                     /product="NADP-dependent succinate-semialdehyde
                     dehydrogenase"
                     /GO_function="GO:0009013 - succinate-semialdehyde
                     dehydrogenase [NAD(P)+] activity [Evidence IEA]"
                     /GO_process="GO:0009450 - gamma-aminobutyric acid
                     catabolic process [Evidence IEA]"
                     /calculated_mol_wt=51717
     Region          1..482
                     /region_name="gabD"
                     /note="NADP-dependent succinate-semialdehyde dehydrogenase
                     I; PRK11241"
                     /db_xref="CDD:183050"
     Site            order(68,77,118,121..122,124..132,138..140,145,227,239,
                     243,246,303,307,353,421,423..424,428,430,433,435..441,447,
                     450..451,457,462,474..480)
                     /site_type="other"
                     /note="tetramerization interface [polypeptide binding]"
                     /db_xref="CDD:143421"
     Site            order(153..157,165,180,182..183,231..234,237,240..241,
                     255..257,289,386,388,414,452)
                     /site_type="other"
                     /note="NAD(P) binding site [chemical binding]"
                     /db_xref="CDD:143421"
     Site            order(157,255,286,289)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143421"
ORIGIN      
        1 mqlndstlfr qqafidgdwr darggdvipv snpangkplg nvpkmgaeet rdainaanra
       61 lpawraltak eranilrrwf nlmmehqddl arlmtleqgk plaeakgeis yaasfiewfa
      121 eegkriygdt ipghqadkrl lvikqpigvt aaitpwnfps amitrkagpa laagctmvlk
      181 pasqtpfsal alaelaqrag ipagvfnvvt gsagdiggel tsnplvrkls ftgsteigrq
      241 lmeqcakdik kvslelggna pfivfddadl dkavegalas kfrnagqtcv canrlyvqdg
      301 vydrfaekln qavnklavgd glqadvaigp lidekavakv qehiadalek garvitggea
      361 hklggnffqp tiladvpdna kvakeetfgp laplfrfsde advirqandt efglaayfya
      421 rdlsrvfrvg ealeygivgi ntgiisneva pfggikasgl gregskygie dyleikymci
      481 gl