MULTISPECIES: SPI-1 type III secretion system effector inositol

LOCUS       WP_001166946             561 aa            linear   BCT 10-JUL-2019
            phosphate phosphatase SopB [Salmonella].
ACCESSION   WP_001166946
VERSION     WP_001166946.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 561)
  AUTHORS   Hernandez,L.D., Hueffer,K., Wenk,M.R. and Galan,J.E.
  TITLE     Salmonella modulates vesicular traffic by altering phosphoinositide
            metabolism
  JOURNAL   Science 304 (5678), 1805-1807 (2004)
   PUBMED   15205533
REFERENCE   2  (residues 1 to 561)
  AUTHORS   Terebiznik,M.R., Vieira,O.V., Marcus,S.L., Slade,A., Yip,C.M.,
            Trimble,W.S., Meyer,T., Finlay,B.B. and Grinstein,S.
  TITLE     Elimination of host cell PtdIns(4,5)P(2) by bacterial SigD promotes
            membrane fission during invasion by Salmonella
  JOURNAL   Nat. Cell Biol. 4 (10), 766-773 (2002)
   PUBMED   12360287
REFERENCE   3  (residues 1 to 561)
  AUTHORS   Marcus,S.L., Wenk,M.R., Steele-Mortimer,O. and Finlay,B.B.
  TITLE     A synaptojanin-homologous region of Salmonella typhimurium SigD is
            essential for inositol phosphatase activity and Akt activation
  JOURNAL   FEBS Lett. 494 (3), 201-207 (2001)
   PUBMED   11311241
REFERENCE   4  (residues 1 to 561)
  AUTHORS   Mirold,S., Ehrbar,K., Weissmuller,A., Prager,R., Tschape,H.,
            Russmann,H. and Hardt,W.D.
  TITLE     Salmonella host cell invasion emerged by acquisition of a mosaic of
            separate genetic elements, including Salmonella pathogenicity
            island 1 (SPI1), SPI5, and sopE2
  JOURNAL   J. Bacteriol. 183 (7), 2348-2358 (2001)
   PUBMED   11244077
REFERENCE   5  (residues 1 to 561)
  AUTHORS   Zhou,D., Chen,L.M., Hernandez,L., Shears,S.B. and Galan,J.E.
  TITLE     A Salmonella inositol polyphosphatase acts in conjunction with
            other bacterial effectors to promote host cell actin cytoskeleton
            rearrangements and bacterial internalization
  JOURNAL   Mol. Microbiol. 39 (2), 248-259 (2001)
   PUBMED   11136447
  REMARK    Erratum:[Mol Microbiol 2001 Jun;40(6):1461]
REFERENCE   6  (residues 1 to 561)
  AUTHORS   Prager,R., Mirold,S., Tietze,E., Strutz,U., Knuppel,B., Rabsch,W.,
            Hardt,W.D. and Tschape,H.
  TITLE     Prevalence and polymorphism of genes encoding translocated effector
            proteins among clinical isolates of Salmonella enterica
  JOURNAL   Int. J. Med. Microbiol. 290 (7), 605-617 (2000)
   PUBMED   11200542
REFERENCE   7  (residues 1 to 561)
  AUTHORS   Hong,K.H. and Miller,V.L.
  TITLE     Identification of a novel Salmonella invasion locus homologous to
            Shigella ipgDE
  JOURNAL   J. Bacteriol. 180 (7), 1793-1802 (1998)
   PUBMED   9537377
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR000648
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..561
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..561
                     /gene="sopB"
     Protein         1..561
                     /product="SPI-1 type III secretion system effector
                     inositol phosphate phosphatase SopB"
                     /calculated_mol_wt=61804
     Region          1..559
                     /region_name="IpgD"
                     /note="Enterobacterial virulence protein IpgD; pfam05925"
                     /db_xref="CDD:283555"
ORIGIN      
        1 mqiqsfyhsa slktqeafks lqktlyngmq ilsgqgkapa kapdarpeii vlrepgatwg
       61 nylqhqkasn hslhnlynlq rdlltvaatv lgkqdpvlts manqmelakv kadrpatkqe
      121 eaaakalkkn lieliaartq qqdglpakea hrfaavafrd aqvkqlnnqp wqtikntlth
      181 nghhytntql paaemkigak difpsayegk gvcswdtkni hhannlwmst vsvhedgkdk
      241 tlfcgirhgv lspyhekdpl lrhvgaenka kevltaalfs kpellnkala geavslklvs
      301 vglltasnif gkegtmvedq mrawqsltqp gkmihlkirn kdgdlqtvki kpdvaafnvg
      361 vnelalklgf glkasdsyna ealhqllgnd lrpearpggw vgewlaqypd nyevvntlar
      421 qikdiwknnq hhkdggepyk laqrlamlah eidavpawnc ksgkdrtgmm dseikreiis
      481 lhqthmlsap gslpdsggqk ifqkvllnsg nleiqkqntg gagnkvmknl spevlnlsyq
      541 krvgdeniwq svkgisslit s