MULTISPECIES: D-erythronate dehydrogenase [Salmonella].

LOCUS       WP_001165740             316 aa            linear   BCT 22-OCT-2023
ACCESSION   WP_001165740
VERSION     WP_001165740.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 316)
  AUTHORS   Zhang,X., Carter,M.S., Vetting,M.W., San Francisco,B., Zhao,S.,
            Al-Obaidi,N.F., Solbiati,J.O., Thiaville,J.J., de Crecy-Lagard,V.,
            Jacobson,M.P., Almo,S.C. and Gerlt,J.A.
  TITLE     Assignment of function to a domain of unknown function: DUF1537 is
            a new kinase family in catabolic pathways for acid sugars
  JOURNAL   Proc Natl Acad Sci U S A 113 (29), E4161-E4169 (2016)
   PUBMED   27402745
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF043036.1
            Evidence Source    :: NCBIFAM
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..316
                     /gene="denD"
     Protein         1..316
                     /product="D-erythronate dehydrogenase"
                     /EC_number="1.1.1.410"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=34045
     Region          1..304
                     /region_name="Gne_like_SDR_e"
                     /note="Escherichia coli Gne (a
                     nucleoside-diphosphate-sugar 4-epimerase)-like, extended
                     (e) SDRs; cd05238"
                     /db_xref="CDD:187549"
     Site            order(7,9..12,32..34,74..76,92,116..118,142,146,169..172)
                     /site_type="other"
                     /note="putative NAD(P) binding site [chemical binding]"
                     /db_xref="CDD:187549"
     Site            order(93,118,142,146)
                     /site_type="active"
                     /db_xref="CDD:187549"
     Site            order(118,142,171,190,202)
                     /site_type="other"
                     /note="putative substrate binding site [chemical binding]"
                     /db_xref="CDD:187549"
ORIGIN      
        1 mqiiitgggg flgqklasal lnsslafnel llvdlkmpar lsdsprlrcl eadltqpgvl
       61 esvitantsv vyhlaaivss haeddfdlgw kvnldltrql leacrrqpqk irfvfsssla
      121 vyggtlpecv tdttaltprs sygaqkaace llvndytrkg yvdglalrlp ticvrpgkpn
      181 raassfvsai ireplqgett vcpvseslrl wisspatvih nlslaatlpa pgeassinlp
      241 gisvtvgeml etlcqaggqa ardrvthqrd egvekivasw pgridnqral algfvadkrf
      301 ddiierfrqd dmegrs