Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: nicotinate-nucleotide--dimethylbenzimidazole


LOCUS       WP_001165576             359 aa            linear   BCT 17-NOV-2023
            phosphoribosyltransferase [Shigella].
ACCESSION   WP_001165576
VERSION     WP_001165576.1
KEYWORDS    RefSeq.
SOURCE      Shigella
  ORGANISM  Shigella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 359)
  AUTHORS   Cheong,C.G., Escalante-Semerena,J.C. and Rayment,I.
  TITLE     Structural investigation of the biosynthesis of alternative lower
            ligands for cobamides by nicotinate mononucleotide:
            5,6-dimethylbenzimidazole phosphoribosyltransferase from Salmonella
            enterica
  JOURNAL   J. Biol. Chem. 276 (40), 37612-37620 (2001)
   PUBMED   11441022
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR03160.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..359
                     /organism="Shigella"
                     /db_xref="taxon:620"
     gene            1..359
                     /gene="cobT"
     Protein         1..359
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /EC_number="2.4.2.21"
                     /GO_function="GO:0008939 -
                     nicotinate-nucleotide-dimethylbenzimidazole
                     phosphoribosyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=36749
     Region          1..351
                     /region_name="CobT"
                     /note="NaMN:DMB phosphoribosyltransferase [Coenzyme
                     transport and metabolism]; COG2038"
                     /db_xref="CDD:441641"
ORIGIN      
        1 mqiiadllnt ipainsaams raqrhvdglf kpvgslgkle alaiqlagmp gvngiphvgk
       61 kavlvmcadh gvweegvais pkevtaiqae nmtrgttgvc vlaaqaganv hvidvgidta
      121 epipglinmr vargsgnias apamsrrqae kllldvicyt relakngvtl fgvgelgman
      181 ttpaaaivst itgrdpeevv giganlptdk lankidvvrr aitlnqpnpq dgvdvlakvg
      241 gfdlvgiagv mlgaascglp vlldgflsya aalaacqmsp aikpylipsh lsaekgaria
      301 lshlglepyl nmdmrlgegs gaalamsiie aacaiynnmg elaasnivlp gnttsdlns