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LOCUS WP_001164582 425 aa linear BCT 24-DEC-2024 ACCESSION WP_001164582 VERSION WP_001164582.1 KEYWORDS RefSeq. SOURCE Escherichia coli ORGANISM Escherichia coli Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. REFERENCE 1 (residues 1 to 425) AUTHORS Goddard,A.D., Bali,S., Mavridou,D.A., Luque-Almagro,V.M., Gates,A.J., Dolores Roldan,M., Newstead,S., Richardson,D.J. and Ferguson,S.J. TITLE The Paracoccus denitrificans NarK-like nitrate and nitrite transporters-probing nitrate uptake and nitrate/nitrite exchange mechanisms JOURNAL Mol Microbiol 103 (1), 117-133 (2017) PUBMED 27696579 REFERENCE 2 (residues 1 to 425) AUTHORS Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P. TITLE Understanding transport by the major facilitator superfamily (MFS): structures pave the way JOURNAL Nat Rev Mol Cell Biol 17 (2), 123-132 (2016) PUBMED 26758938 REFERENCE 3 (residues 1 to 425) AUTHORS Fukuda,M., Takeda,H., Kato,H.E., Doki,S., Ito,K., Maturana,A.D., Ishitani,R. and Nureki,O. TITLE Structural basis for dynamic mechanism of nitrate/nitrite antiport by NarK JOURNAL Nat Commun 6, 7097 (2015) PUBMED 25959928 REMARK Publication Status: Online-Only REFERENCE 4 (residues 1 to 425) AUTHORS Yan,N. TITLE Structural Biology of the Major Facilitator Superfamily Transporters JOURNAL Annu Rev Biophys 44, 257-283 (2015) PUBMED 26098515 REFERENCE 5 (residues 1 to 425) AUTHORS Yan,N. TITLE Structural advances for the major facilitator superfamily (MFS) transporters JOURNAL Trends Biochem Sci 38 (3), 151-159 (2013) PUBMED 23403214 REFERENCE 6 (residues 1 to 425) AUTHORS Jia,W., Tovell,N., Clegg,S., Trimmer,M. and Cole,J. TITLE A single channel for nitrate uptake, nitrite export and nitrite uptake by Escherichia coli NarU and a role for NirC in nitrite export and uptake JOURNAL Biochem J 417 (1), 297-304 (2009) PUBMED 18691156 REFERENCE 7 (residues 1 to 425) AUTHORS Law,C.J., Maloney,P.C. and Wang,D.N. TITLE Ins and outs of major facilitator superfamily antiporters JOURNAL Annu Rev Microbiol 62, 289-305 (2008) PUBMED 18537473 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: Conserved Domain (CDD) Evidence Accession :: Domain architecture ID 11454872 Evidence Source :: NCBI SPARCLE ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..425 /organism="Escherichia coli" /db_xref="taxon:562" Protein 1..425 /product="MFS transporter" /GO_function="GO:0015112 - nitrate transmembrane transporter activity [Evidence IEA]" /GO_function="GO:0022857 - transmembrane transporter activity [Evidence IEA]" /GO_process="GO:0055085 - transmembrane transport [Evidence IEA]" /calculated_mol_wt=46685 Region 7..418 /region_name="NarK" /note="Nitrate/nitrite transporter NarK [Inorganic ion transport and metabolism]; COG2223" /db_xref="CDD:441825" ORIGIN 1 mqhnsyrrwi tlaiisfsgg vsfdlaylry iyqipmakfm gfsnteigli mstfgiaaii 61 lyapsgviad kfshrkmits amiitgllgl lmatypplwv mlciqvafai ttilmlwsvs 121 ikaasllgdh seqgkimgwm eglrgvgvms lavftmwvfs rfapddstsl ktviiiysvv 181 yillgilcwf fvsdnnnlrs anneekqsfq lsdilavlri sttwycsmvi fgvftiyail 241 systnyltem ygmslvaasy mgivinkifr alcgplggii ttyskvkspt rviqilsvlg 301 llaltallvt nsnpqsvamg iglilllgft cyasrglywa cpgeartpsy imgttvgics 361 vigflpdvfv ypiighwqdt qpaaeayrnm wlmgmaalam vivftfllfq kirtadsapa 421 massk