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choline dehydrogenase [Escherichia coli].


LOCUS       WP_001159114             562 aa            linear   BCT 08-OCT-2019
ACCESSION   WP_001159114
VERSION     WP_001159114.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 562)
  AUTHORS   Rosenstein,R., Futter-Bryniok,D. and Gotz,F.
  TITLE     The choline-converting pathway in Staphylococcus xylosus C2A:
            genetic and physiological characterization
  JOURNAL   J. Bacteriol. 181 (7), 2273-2278 (1999)
   PUBMED   10094709
REFERENCE   2  (residues 1 to 562)
  AUTHORS   Pocard,J.A., Vincent,N., Boncompagni,E., Smith,L.T., Poggi,M.C. and
            Le Rudulier,D.
  TITLE     Molecular characterization of the bet genes encoding glycine
            betaine synthesis in Sinorhizobium meliloti 102F34
  JOURNAL   Microbiology (Reading, Engl.) 143 (Pt 4), 1369-1379 (1997)
   PUBMED   9141699
REFERENCE   3  (residues 1 to 562)
  AUTHORS   Boch,J., Kempf,B., Schmid,R. and Bremer,E.
  TITLE     Synthesis of the osmoprotectant glycine betaine in Bacillus
            subtilis: characterization of the gbsAB genes
  JOURNAL   J. Bacteriol. 178 (17), 5121-5129 (1996)
   PUBMED   8752328
REFERENCE   4  (residues 1 to 562)
  AUTHORS   van Beilen,J.B., Eggink,G., Enequist,H., Bos,R. and Witholt,B.
  TITLE     DNA sequence determination and functional characterization of the
            OCT-plasmid-encoded alkJKL genes of Pseudomonas oleovorans
  JOURNAL   Mol. Microbiol. 6 (21), 3121-3136 (1992)
   PUBMED   1453953
REFERENCE   5  (residues 1 to 562)
  AUTHORS   Andresen,P.A., Kaasen,I., Styrvold,O.B., Boulnois,G. and Strom,A.R.
  TITLE     Molecular cloning, physical mapping and expression of the bet genes
            governing the osmoregulatory choline-glycine betaine pathway of
            Escherichia coli
  JOURNAL   J. Gen. Microbiol. 134 (6), 1737-1746 (1988)
   PUBMED   3065456
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01810.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..562
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..562
                     /gene="betA"
     Protein         1..562
                     /product="choline dehydrogenase"
                     /EC_number="1.1.99.1"
                     /GO_function="GO:0008812 - choline dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019285 - glycine betaine biosynthetic
                     process from choline [Evidence IEA]"
                     /calculated_mol_wt=62502
     Region          1..557
                     /region_name="PRK02106"
                     /note="choline dehydrogenase; Validated"
                     /db_xref="CDD:235000"
ORIGIN      
        1 mqfdyiiiga gsagnvlatr ltedpntsvl lleaggpdyr fdfrtqmpaa lafplqgkry
       61 nwayetepep fmnnrrmecg rgkglggssl ingmcyirgn amdldnwake pglenwsyld
      121 clpyyrkaet rdvgendyhg gdgpvsvtts kpgvnplfea mieagvqagy prtddlngyq
      181 qegfgpmdrt vtpqgrrast argyldqaks rpnltirtha mtdhiifdck ravgvewleg
      241 dstiptrata nkevllcaga iaspqilqrs gvgnaellae fdiplvhdlp gvgenlqdhl
      301 emylqyecke pvslypalqw wnqpkigaew lfggtgvgas nhfeaggfir sreefawpni
      361 qyhflpvain yngsnavkeh gfqchvgsmr spsrghvrik srdphqhpai lfnymsheqd
      421 wqefrdairi treimhqpal dqyrgreisp gtecqtdeql defvrnhaet afhpcgtckm
      481 gydemsvvdg egrvhglegl rvvdasimpq iitgnlnatt imigekmadm irgkealprs
      541 tagyfvangm pvrakkmsrd ln