MULTISPECIES: two-component system response regulator OmpR

LOCUS       WP_001157751             239 aa            linear   BCT 17-NOV-2023
            [Enterobacterales].
ACCESSION   WP_001157751
VERSION     WP_001157751.1
KEYWORDS    RefSeq.
SOURCE      Enterobacterales
  ORGANISM  Enterobacterales
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria.
REFERENCE   1  (residues 1 to 239)
  AUTHORS   Nieckarz,M., Raczkowska,A., Jaworska,K., Stefanska,E., Skorek,K.,
            Stosio,D. and Brzostek,K.
  TITLE     The Role of OmpR in the Expression of Genes of the KdgR Regulon
            Involved in the Uptake and Depolymerization of Oligogalacturonides
            in Yersinia enterocolitica
  JOURNAL   Front Cell Infect Microbiol 7, 366 (2017)
   PUBMED   28861396
REFERENCE   2  (residues 1 to 239)
  AUTHORS   Raczkowska,A., Trzos,J., Lewandowska,O., Nieckarz,M. and
            Brzostek,K.
  TITLE     Expression of the AcrAB Components of the AcrAB-TolC Multidrug
            Efflux Pump of Yersinia enterocolitica Is Subject to Dual
            Regulation by OmpR
  JOURNAL   PLoS ONE 10 (4), e0124248 (2015)
   PUBMED   25893523
REFERENCE   3  (residues 1 to 239)
  AUTHORS   Reboul,A., Lemaitre,N., Titecat,M., Merchez,M., Deloison,G.,
            Ricard,I., Pradel,E., Marceau,M. and Sebbane,F.
  TITLE     Yersinia pestis requires the 2-component regulatory system
            OmpR-EnvZ to resist innate immunity during the early and late
            stages of plague
  JOURNAL   J. Infect. Dis. 210 (9), 1367-1375 (2014)
   PUBMED   24813471
REFERENCE   4  (residues 1 to 239)
  AUTHORS   Gao,H., Zhang,Y., Han,Y., Yang,L., Liu,X., Guo,Z., Tan,Y.,
            Huang,X., Zhou,D. and Yang,R.
  TITLE     Phenotypic and transcriptional analysis of the osmotic regulator
            OmpR in Yersinia pestis
  JOURNAL   BMC Microbiol. 11, 39 (2011)
   PUBMED   21345178
REFERENCE   5  (residues 1 to 239)
  AUTHORS   Maris,A.E., Walthers,D., Mattison,K., Byers,N. and Kenney,L.J.
  TITLE     The response regulator OmpR oligomerizes via beta-sheets to form
            head-to-head dimers
  JOURNAL   J. Mol. Biol. 350 (5), 843-856 (2005)
   PUBMED   15979641
REFERENCE   6  (residues 1 to 239)
  AUTHORS   Martinez-Hackert,E. and Stock,A.M.
  TITLE     The DNA-binding domain of OmpR: crystal structures of a winged
            helix transcription factor
  JOURNAL   Structure 5 (1), 109-124 (1997)
   PUBMED   9016718
REFERENCE   7  (residues 1 to 239)
  AUTHORS   Kondo,H., Nakagawa,A., Nishihira,J., Nishimura,Y., Mizuno,T. and
            Tanaka,I.
  TITLE     Escherichia coli positive regulator OmpR has a large loop structure
            at the putative RNA polymerase interaction site
  JOURNAL   Nat. Struct. Biol. 4 (1), 28-31 (1997)
   PUBMED   8989318
REFERENCE   8  (residues 1 to 239)
  AUTHORS   Tsuzuki,M., Aiba,H. and Mizuno,T.
  TITLE     Gene activation by the Escherichia coli positive regulator, OmpR.
            Phosphorylation-independent mechanism of activation by an OmpR
            mutant
  JOURNAL   J. Mol. Biol. 242 (5), 607-613 (1994)
   PUBMED   7932717
REFERENCE   9  (residues 1 to 239)
  AUTHORS   Jo,Y.L., Nara,F., Ichihara,S., Mizuno,T. and Mizushima,S.
  TITLE     Purification and characterization of the OmpR protein, a positive
            regulator involved in osmoregulatory expression of the ompF and
            ompC genes in Escherichia coli
  JOURNAL   J. Biol. Chem. 261 (32), 15252-15256 (1986)
   PUBMED   3533941
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007005.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK09468
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..239
                     /organism="Enterobacterales"
                     /db_xref="taxon:91347"
     gene            1..239
                     /gene="ompR"
     Protein         1..239
                     /product="two-component system response regulator OmpR"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of transcription,
                     DNA-templated [Evidence IEA]"
                     /calculated_mol_wt=27223
     Region          1..238
                     /region_name="ompR"
                     /note="osmolarity response regulator; Provisional;
                     PRK09468"
                     /db_xref="CDD:181883"
ORIGIN      
        1 mqenykilvv dddmrlrall erylteqgfq vrsvanaeqm drlltresfh lmvldlmlpg
       61 edglsicrrl rsqsnpmpii mvtakgeevd rivgleigad dyipkpfnpr ellariravl
      121 rrqanelpga psqeeaviaf gkfklnlgtr emfredepmp ltsgefavlk alvshprepl
      181 srdklmnlar greysamers idvqisrlrr mveedpahpr yiqtvwglgy vfvpdgska