pyrimidine utilization protein A [Shigella flexneri].

LOCUS       WP_001149962             382 aa            linear   BCT 13-AUG-2024
ACCESSION   WP_001149962
VERSION     WP_001149962.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 382)
  AUTHORS   Loh,K.D., Gyaneshwar,P., Markenscoff Papadimitriou,E., Fong,R.,
            Kim,K.S., Parales,R., Zhou,Z., Inwood,W. and Kustu,S.
  TITLE     A previously undescribed pathway for pyrimidine catabolism
  JOURNAL   Proc Natl Acad Sci U S A 103 (13), 5114-5119 (2006)
   PUBMED   16540542
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR03612.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     gene            1..382
                     /gene="rutA"
     Protein         1..382
                     /product="pyrimidine utilization protein A"
                     /EC_number="1.14.99.46"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /calculated_mol_wt=42096
     Region          20..374
                     /region_name="RutA"
                     /note="pyrimidine utilization protein A; TIGR03612"
                     /db_xref="CDD:163355"
     Site            order(25,29,83,136,159,209..210,224,259,261)
                     /site_type="active"
                     /db_xref="CDD:238527"
     Site            order(80..85,88,91..92,95,112,114..115,118..119,122,125,
                     142,145..146,187..190,192..193)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238527"
     Site            105..106
                     /site_type="active"
                     /note="non-prolyl cis peptide bond [active]"
                     /db_xref="CDD:238527"
     Site            order(138..146,153..154,158,186..198,262..265,272..277)
                     /site_type="other"
                     /note="insertion regions"
                     /db_xref="CDD:238527"
ORIGIN      
        1 mqdaaprltf tlrdeerlmm kigvfvpign ngwlisthap qymptfelnk aiaqkaehyh
       61 fdfalsmikl rgfggktefw dhnlesftlm aglaavtsri qiyataatlt lppaivarma
      121 atidsisggr fgvnlvtgwq kpeyeqmgiw pgddyfsrry dylteyvqvl rdlwgtgksd
      181 fkgdfftmnd crvspqpsip mkvicagqsd agmafsaqya dfnfcfgkgv ntptafapta
      241 armkqateqt grdvgsyvlf mviadetdda trakwehyka gadeealswl teqsqkdtrs
      301 gtdtnvrqma dptsavninm gtlvgsyasv armldevasv pgaegvlltf ddflsgietf
      361 geriqplmqc rahlsaltqe va