MULTISPECIES: 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC

LOCUS       WP_001149781             376 aa            linear   BCT 17-JUN-2024
            [Salmonella].
ACCESSION   WP_001149781
VERSION     WP_001149781.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 376)
  AUTHORS   Madsen,C.T., Mengel-Jorgensen,J., Kirpekar,F. and Douthwaite,S.
  TITLE     Identifying the methyltransferases for m(5)U747 and m(5)U1939 in
            23S rRNA using MALDI mass spectrometry
  JOURNAL   Nucleic Acids Res 31 (16), 4738-4746 (2003)
   PUBMED   12907714
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02085.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..376
                     /gene="rlmC"
     Protein         1..376
                     /product="23S rRNA (uracil(747)-C(5))-methyltransferase
                     RlmC"
                     /EC_number="2.1.1.189"
                     /GO_function="GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016070 - RNA metabolic process [Evidence
                     IEA]"
                     /calculated_mol_wt=42049
     Region          2..374
                     /region_name="AdoMet_MTases"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); cl17173"
                     /db_xref="CDD:473071"
     Site            order(240..246,262..263,288..290,307)
                     /site_type="other"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]"
                     /db_xref="CDD:100107"
ORIGIN      
        1 mqcalydagr crscqwitqs vneqlsakta dlhrllaglp veqwcapigg peqhfrnkak
       61 mvvsgsvekp lfgmlhrdgt pvdlcgcply pasfdpvfsa lkpfiaragl tpynvarkrg
      121 elkyllltes qfdggmmlrf vlrsetkltq lraalpwlra qlpqlrvita niqpvhmaim
      181 egeteiyltd qqalaerfnd vplwirpqsf fqtnptvasr lyatardwvg qlpvrhmwdl
      241 fcgvggfglh catpqmqltg ieiapeaiac akqsaaelgl trlhfqalds tqfataqget
      301 pdlvlvnppr rgigkplcdy laqmaprfii ysscnaqtma qdirhlpnyr iqrvqlfdmf
      361 phtahyevla llrrsi