23S rRNA (uracil(747)-C(5))-methyltransferase RlmC [Escherichia

LOCUS       WP_001149719             375 aa            linear   BCT 17-JUN-2024
            coli].
ACCESSION   WP_001149719
VERSION     WP_001149719.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 375)
  AUTHORS   Madsen,C.T., Mengel-Jorgensen,J., Kirpekar,F. and Douthwaite,S.
  TITLE     Identifying the methyltransferases for m(5)U747 and m(5)U1939 in
            23S rRNA using MALDI mass spectrometry
  JOURNAL   Nucleic Acids Res 31 (16), 4738-4746 (2003)
   PUBMED   12907714
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02085.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..375
                     /gene="rlmC"
     Protein         1..375
                     /product="23S rRNA (uracil(747)-C(5))-methyltransferase
                     RlmC"
                     /EC_number="2.1.1.189"
                     /GO_function="GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016070 - RNA metabolic process [Evidence
                     IEA]"
                     /calculated_mol_wt=41829
     Region          2..374
                     /region_name="meth_trns_rumB"
                     /note="23S rRNA (uracil-5-)-methyltransferase RumB;
                     TIGR02085"
                     /db_xref="CDD:131140"
     Site            order(240..246,262..263,288..290,307)
                     /site_type="other"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]"
                     /db_xref="CDD:100107"
ORIGIN      
        1 mqcalydagr crscqwitqp ipeqlsakta dlknlladfp veewcapvsg peqgfrnkak
       61 mvvsgsvekp llgmlhrdgt pedlcdcply pasfapvfaa lkpfiaragl tpynvarkrg
      121 elkyilltes qsdggmmlrf vlrsetklaq lrkalpwlqa qlpqlkvitv niqpvhmaim
      181 egeteiylte qqalverfnd vplwirpqsf fqtnpavasq lyatardwvr qlpvkhmwdl
      241 fcgvggfglh catpdmqltg ieialeaiac akqsaaelgl trlqfqalds tqfataqgev
      301 pelvlvnppr rgigkplcdy lstmaprfii ysscnaqtma kdirelpgyr iervqlfdmf
      361 phtahyevlt llvkm