MULTISPECIES: 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC

LOCUS       WP_001149682             375 aa            linear   BCT 17-JUN-2024
            [Enterobacteriaceae].
ACCESSION   WP_001149682
VERSION     WP_001149682.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 375)
  AUTHORS   Madsen,C.T., Mengel-Jorgensen,J., Kirpekar,F. and Douthwaite,S.
  TITLE     Identifying the methyltransferases for m(5)U747 and m(5)U1939 in
            23S rRNA using MALDI mass spectrometry
  JOURNAL   Nucleic Acids Res 31 (16), 4738-4746 (2003)
   PUBMED   12907714
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02085.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..375
                     /gene="rlmC"
     Protein         1..375
                     /product="23S rRNA (uracil(747)-C(5))-methyltransferase
                     RlmC"
                     /EC_number="2.1.1.189"
                     /GO_function="GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016070 - RNA metabolic process [Evidence
                     IEA]"
                     /calculated_mol_wt=41825
     Region          2..374
                     /region_name="meth_trns_rumB"
                     /note="23S rRNA (uracil-5-)-methyltransferase RumB;
                     TIGR02085"
                     /db_xref="CDD:131140"
     Site            order(240..246,262..263,288..290,307)
                     /site_type="other"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]"
                     /db_xref="CDD:100107"
ORIGIN      
        1 mqcalydagr crscqwimqp ipeqlsakta dlknlladfp veewcapvsg peqgfrnkak
       61 mvvsgsvekp llgmlhrdgt pedlcdcply pasfapvfaa lkpfiaragl tpynvarkrg
      121 elkyilltes qsdggmmlrf vlrsdtklaq lrkalpwlhe qlpqlkvitv niqpvhmaim
      181 egeteiylte qqalaerfnd vplwirpqsf fqtnpavasq lyatardwvr qlpvkhmwdl
      241 fcgvggfglh catpdmqltg ieiaseaiac akqsaaelgl trlqfqalds tqfataqgdv
      301 pelvlvnppr rgigkplcdy lstmaprfii ysscnaqtma kdirelpgfr iervqlfdmf
      361 phtahyevlt llvkq