MULTISPECIES: alanine racemase [Enterobacteriaceae].

LOCUS       WP_001147332             359 aa            linear   BCT 09-JUN-2024
ACCESSION   WP_001147332
VERSION     WP_001147332.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00492.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..359
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..359
                     /gene="alr"
     Protein         1..359
                     /product="alanine racemase"
                     /EC_number="5.1.1.1"
                     /GO_function="GO:0008784 - alanine racemase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006522 - alanine metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=39064
     Region          3..358
                     /region_name="PLPDE_III_AR_proteobact"
                     /note="Type III Pyridoxal 5-phosphate (PLP)-Dependent
                     Enzymes, Proteobacterial Alanine Racemases; cd06827"
                     /db_xref="CDD:143500"
     Site            order(32,34,38,78,122,129,157,159,193..195,209..212,343)
                     /site_type="active"
                     /db_xref="CDD:143500"
     Site            order(32,34,38,78,159,193..194,209,211..212,343)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate (PLP) binding site [chemical
                     binding]"
                     /db_xref="CDD:143500"
     Site            order(34,38,129,159,343)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:143500"
     Site            order(34,255)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143500"
     Site            order(242,245,251..252,254..256,269,274,280,302,304,341,
                     343..344,349,352)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:143500"
ORIGIN      
        1 mqaatvvinr ralrhnlqrl relapaskmv avvkanaygh glletartlp dadafgvarl
       61 eealrlragg itkpvllleg ffdardlpti saqhfhtavh neeqlaalee asldepvtvw
      121 mkldtgmhrl gvrpeqaeaf yhrltqcknv rqpvnivshf aradepkcga tekqlaifnt
      181 fcegkpgqrs iaasggillw pqshfdwvrp giilygvspl edrstgadfg cqpvmsltss
      241 liavrehkvg epvgyggtwi serdtrlgvv amgygdgypr aapsgtpvlv ngrevpivgr
      301 vamdmicvdl gpqaqdkagd pvilwgeglp veriaemtkv sayelitrlt srvamkyvd