MULTISPECIES: 3-isopropylmalate dehydratase large subunit

LOCUS       WP_001140629             466 aa            linear   BCT 01-JUL-2024
            [Salmonella].
ACCESSION   WP_001140629
VERSION     WP_001140629.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00170.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..466
                     /gene="leuC"
     Protein         1..466
                     /product="3-isopropylmalate dehydratase large subunit"
                     /EC_number="4.2.1.33"
                     /GO_component="GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA]"
                     /GO_function="GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster
                     binding [Evidence IEA]"
                     /GO_process="GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=49655
     Region          1..466
                     /region_name="PRK05478"
                     /note="3-isopropylmalate dehydratase large subunit"
                     /db_xref="CDD:235490"
     Site            order(33,36,128..129,411,430,435)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:153133"
     Site            order(130,347,407,410..411,429)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:153133"
ORIGIN      
        1 maktlyeklf dahvvfeapn etpllyidrh lvhevtspqa fdglrahhrp vrqpgktfat
       61 mdhnvstqtk dinasgemar iqmqeliknc nefgvelydl nhpyqgivhv mgpeqgvtlp
      121 gmtivcgdsh tathgafgal afgigtseve hvlatqtlkq graktmkiev tgnaapgita
      181 kdivlaiigk tgsaggtghv vefcgdaira lsmegrmtlc nmaiemgaka glvapdettf
      241 nyvkgrlhap kgrdfdeave ywktlktddg atfdtvvalr aeeiapqvtw gtnpgqvisv
      301 tdiipdpasf sdpverasae kalaymglqp gvpltdvaid kvfigsctns riedlraaae
      361 vakgrkvapg vqalvvpgsg pvkaqaeaeg ldkifieagf ewrlpgcsmc lamnndrlnp
      421 gercastsnr nfegrqgrgg rthlvspama aaaavtghfa dirsik