MULTISPECIES: NAD-dependent dihydropyrimidine dehydrogenase subunit

LOCUS       WP_001136325             412 aa            linear   BCT 17-NOV-2023
            PreT [Shigella].
ACCESSION   WP_001136325
VERSION     WP_001136325.1
KEYWORDS    RefSeq.
SOURCE      Shigella
  ORGANISM  Shigella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 412)
  AUTHORS   Hidese,R., Mihara,H., Kurihara,T. and Esaki,N.
  TITLE     Escherichia coli dihydropyrimidine dehydrogenase is a novel
            NAD-dependent heterotetramer essential for the production of
            5,6-dihydrouracil
  JOURNAL   J Bacteriol 193 (4), 989-993 (2011)
   PUBMED   21169495
REFERENCE   2  (residues 1 to 412)
  AUTHORS   Mihara,H., Hidese,R., Yamane,M., Kurihara,T. and Esaki,N.
  TITLE     The iscS gene deficiency affects the expression of pyrimidine
            metabolism genes
  JOURNAL   Biochem Biophys Res Commun 372 (3), 407-411 (2008)
   PUBMED   18482579
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011270
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Shigella"
                     /db_xref="taxon:620"
     gene            1..412
                     /gene="preT"
     Protein         1..412
                     /product="NAD-dependent dihydropyrimidine dehydrogenase
                     subunit PreT"
                     /EC_number="1.3.1.1"
                     /calculated_mol_wt=44266
     Region          3..412
                     /region_name="PRK11749"
                     /note="dihydropyrimidine dehydrogenase subunit A;
                     Provisional"
                     /db_xref="CDD:236967"
ORIGIN      
        1 mpqqnyldel tpaftpllai keasrcllch dapcsqacpa qtdpgkfirs iyfrnfkgaa
       61 etirennalg avcarvcpte klcqsgctra gvdapidigr lqrfvtdfeq qtgmeiyqpg
      121 tktlgkvaii gagpaglqas vtltnqgydv tiyekeahpg gwlrngipqf rlpqsvldae
      181 iariekmgvt ikcnneigkt ltleqlkaen ravlvtvgls sgsglplfeh sdveiavdfl
      241 qrvrqaqgdi sipqsaliig ggdvamdvas tlkvlgcqav tcvareelde fpasekefas
      301 arelgvsiid gftpvavegn kvtfkhvrls geltmaadki ilavgqharl dafaeleqqr
      361 ntiktqnyqt rdpqvfaagd ivegdktvvy avktgkeaae aihhylegac sc