MULTISPECIES: bifunctional nicotinamidase/pyrazinamidase

LOCUS       WP_001135066             213 aa            linear   BCT 04-SEP-2023
            [Enterobacteriaceae].
ACCESSION   WP_001135066
VERSION     WP_001135066.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 213)
  AUTHORS   Wang,X., Liu,B., Dou,Y., Fan,H., Wang,S., Li,T., Ding,C. and Yu,S.
  TITLE     The Riemerella anatipestifer AS87_01735 Gene Encodes Nicotinamidase
            PncA, an Important Virulence Factor
  JOURNAL   Appl Environ Microbiol 82 (19), 5815-5823 (2016)
   PUBMED   27451449
  REMARK    Publication Status: Online-Only
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008623.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11609
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..213
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..213
                     /gene="pncA"
     Protein         1..213
                     /product="bifunctional nicotinamidase/pyrazinamidase"
                     /EC_number="3.5.1.-"
                     /EC_number="3.5.1.19"
                     /calculated_mol_wt=23231
     Region          4..213
                     /region_name="PRK11609"
                     /note="bifunctional nicotinamidase/pyrazinamidase"
                     /db_xref="CDD:183228"
     Site            order(10,111,156)
                     /site_type="active"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:238493"
     Site            order(52,54,86)
                     /site_type="metal-binding"
                     /note="metal binding site [ion binding]"
                     /db_xref="CDD:238493"
     Site            151..152
                     /site_type="active"
                     /note="conserved cis-peptide bond [active]"
                     /db_xref="CDD:238493"
ORIGIN      
        1 mppralllvd lqndfcagga lavpegdstv dvanrlidwc qsrgeavias qdwhpanhgs
       61 fasqhgvepy tpgqldglpq tfwpdhcvqn segaqlhpll hqkaiaavfh kgenplvdsy
      121 saffdngrrq ktslddwlrd heidelivmg latdycvkft vldalqlgyk vnvitdgcrg
      181 vniqpqdsah afmemsaaga tlytladwee tqg