Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: type I DNA topoisomerase [Salmonella].


LOCUS       WP_001129708             180 aa            linear   BCT 19-MAR-2023
ACCESSION   WP_001129708
VERSION     WP_001129708.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 180)
  AUTHORS   Forterre,P. and Gadelle,D.
  TITLE     Phylogenomics of DNA topoisomerases: their origin and putative
            roles in the emergence of modern organisms
  JOURNAL   Nucleic Acids Res 37 (3), 679-692 (2009)
   PUBMED   19208647
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11425664
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..180
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     Protein         1..180
                     /product="type I DNA topoisomerase"
                     /EC_number="5.6.2.1"
                     /GO_function="GO:0003917 - DNA topoisomerase type I
                     (single strand cut, ATP-independent) activity [Evidence
                     IEA]"
                     /calculated_mol_wt=19859
     Region          <12..87
                     /region_name="YrdD"
                     /note="DNA topoisomerase I, ssDNA-binding Zn-finger and
                     Zn-ribbon domains [Replication, recombination and repair];
                     COG0551"
                     /db_xref="CDD:440317"
     Region          <54..175
                     /region_name="YrdD"
                     /note="DNA topoisomerase I, ssDNA-binding Zn-finger and
                     Zn-ribbon domains [Replication, recombination and repair];
                     COG0551"
                     /db_xref="CDD:440317"
ORIGIN      
        1 maksalfsvr knepcpqcga elvirsgkhg pflgcsrype cdyvrplksq adghivkile
       61 gqlcpecgav lvlrqgrfgm figcsqypqc ehtvvidkpd etaiacpacq qghlvqrrsr
      121 ygkifhscdr ypecqfvinf tpvagecpec hyplliekkt aqgvkrfcas kqcgkpvpve