MULTISPECIES: MFS transporter [Salmonella].

LOCUS       WP_001127538             391 aa            linear   BCT 28-JUL-2024
ACCESSION   WP_001127538
VERSION     WP_001127538.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 391)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 391)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13023516
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..391
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     Protein         1..391
                     /product="MFS transporter"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=40498
     Region          5..376
                     /region_name="MFS_NepI_like"
                     /note="Purine ribonucleoside efflux pump NepI and similar
                     transporters of the Major Facilitator Superfamily;
                     cd17324"
                     /db_xref="CDD:340882"
     Site            order(15..16,19..20,23,55,105..106,108..110,113,133,
                     136..137,140,209,212..213,216..218,221,249,253,303..304,
                     308,312,331,334..335,338..339,342)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340882"
ORIGIN      
        1 mplalfalti safaigttef vivglvptia qqlaislpsa gmlvsiyalg vaigapvlta
       61 ltgrlprkql lvalmvlfta gnllawqapg ymtlivarll tglahgvffs igstiatslv
      121 pkekaasaia imfggltval vtgvplgtfi gqhfgwretf lavsllgvia lmssqllipa
      181 nipgraaasi rdqvkvlthp rllliyavta lgyggvftaf tflapmmqdl agfspaavsw
      241 illgygvsva igniwggkla dkhgavpalk fifaalfvll mvfqvtastq yaalatilvm
      301 gvfafgnvpg lqvyvvqkae qftpnavdva sglniaafni gialgsvigg qtvehyglaq
      361 tpwigalivl vafllmgvsg rldkpvrial e