MULTISPECIES: homoserine O-acetyltransferase MetA [Escherichia].

LOCUS       WP_001122779             309 aa            linear   BCT 13-JAN-2025
ACCESSION   WP_001122779
VERSION     WP_001122779.1
KEYWORDS    RefSeq.
SOURCE      Escherichia
  ORGANISM  Escherichia
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 309)
  AUTHORS   Bastard,K., Perret,A., Mariage,A., Bessonnet,T., Pinet-Turpault,A.,
            Petit,J.L., Darii,E., Bazire,P., Vergne-Vaxelaire,C., Brewee,C.,
            Debard,A., Pellouin,V., Besnard-Gonnet,M., Artiguenave,F.,
            Medigue,C., Vallenet,D., Danchin,A., Zaparucha,A., Weissenbach,J.,
            Salanoubat,M. and de Berardinis,V.
  TITLE     Parallel evolution of non-homologous isofunctional enzymes in
            methionine biosynthesis
  JOURNAL   Nat Chem Biol 13 (8), 858-866 (2017)
   PUBMED   28581482
  REMARK    Erratum:[Nat Chem Biol. 2017 Sep 19;13(10):1137. doi:
            10.1038/nchembio1017-1137c. PMID: 28926556]
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF047918.2
            Evidence Source    :: NCBIFAM
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Escherichia"
                     /db_xref="taxon:561"
     gene            1..309
                     /gene="metA"
     Protein         1..309
                     /product="homoserine O-acetyltransferase MetA"
                     /EC_number="2.3.1.31"
                     /GO_function="GO:0004414 - homoserine O-acetyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=35596
     Region          1..302
                     /region_name="PRK05368"
                     /note="homoserine O-succinyltransferase; Provisional"
                     /db_xref="CDD:235433"
     Site            47
                     /site_type="active"
                     /note="proposed active site lysine [active]"
                     /db_xref="CDD:153225"
     Site            142
                     /site_type="active"
                     /note="conserved cys residue [active]"
                     /db_xref="CDD:153225"
ORIGIN      
        1 mpirvpdelp avnflreenv fvmttsrasg qeirplkvli lnlmpkkiet enqflrllsn
       61 splqvdiqll ridsresrnt paehlnnfyc nfediqdqnf dglivtgapl glvefndvay
      121 wpqikqvlew skdhvtstlf vcwavqaaln ilygipkqtr teklsgvyeh hilhphallt
      181 rgfddsflap hsryadfpaa lirdytdlei laeteegday lfaskdkria fvtghpeyda
      241 qtlaqeffrd veagldpdvp ynyfphndpq ntpraswrsh gnllftnwln yyvyqitpyd
      301 lrhmnptld