MULTISPECIES: diaminopimelate decarboxylase [Shigella].

LOCUS       WP_001120740             420 aa            linear   BCT 17-NOV-2023
ACCESSION   WP_001120740
VERSION     WP_001120740.1
KEYWORDS    RefSeq.
SOURCE      Shigella
  ORGANISM  Shigella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01048.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Shigella"
                     /db_xref="taxon:620"
     gene            1..420
                     /gene="lysA"
     Protein         1..420
                     /product="diaminopimelate decarboxylase"
                     /EC_number="4.1.1.20"
                     /GO_function="GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /calculated_mol_wt=46044
     Region          2..411
                     /region_name="lysA"
                     /note="diaminopimelate decarboxylase; TIGR01048"
                     /db_xref="CDD:273415"
     Site            order(52,54,73,100,142,189,191,194,226..227,268..271,307,
                     311,342,378,382,386)
                     /site_type="active"
                     /db_xref="CDD:143501"
     Site            order(52,54,73,100,142,189,191,194,226..227,268..271,342,
                     378)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate (PLP) binding site [chemical
                     binding]"
                     /db_xref="CDD:143501"
     Site            order(54,191,194,271,307,311,342..343,378,382,386)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:143501"
     Site            order(54,342)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143501"
     Site            order(59..60,75..76,78..79,102..104,108,122,125,162..165,
                     286,288,295,297,339..344,346,381..383,385..388,391)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:143501"
ORIGIN      
        1 mphslfstdt dltaenllrl paefgcpvwv ydaqiirrqi aalkqfevvr faqkacsnih
       61 ilrlmreqgv kvdsvslgei eralaagynp qthpddivft advidqatle rvselqipvn
      121 agsvdtldql gqvspghrvw lrvnpgfghg hsqktntgge nskhgiwytd lpaaldviqr
      181 hhlqlvgihm higsgvdyah leqvcgamvr qviefgqdlq aisaggglsi pyqqgeeavd
      241 tehyyglwna areqiarhlg hpvkleiepg rflvaqsgvl itqvrsvkqm gsrhfvlvda
      301 gfndlmrpam ygsyhhisal aadgrsleha ptvetvvagp lcesgdvftq qeggnvetra
      361 lpevkagdyl vlhdtgayga smssnynsrp llpevlfdng qarlirrrqt ieellalell