hydroxycarboxylate dehydrogenase HcxA [Escherichia coli].

LOCUS       WP_001120445             362 aa            linear   BCT 10-JUL-2019
ACCESSION   WP_001120445
VERSION     WP_001120445.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 362)
  AUTHORS   Sevin,D.C., Fuhrer,T., Zamboni,N. and Sauer,U.
  TITLE     Nontargeted in vitro metabolomics for high-throughput
            identification of novel enzymes in Escherichia coli
  JOURNAL   Nat. Methods 14 (2), 187-194 (2017)
   PUBMED   27941785
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR008059
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..362
                     /gene="hcxA"
     Protein         1..362
                     /product="hydroxycarboxylate dehydrogenase HcxA"
                     /EC_number="1.1.1.-"
                     /calculated_mol_wt=38888
     Region          1..362
                     /region_name="PRK10586"
                     /note="putative oxidoreductase; Provisional"
                     /db_xref="CDD:182570"
     Site            order(42,95..97,100,103,118..119,121,140..141,158,166,173,
                     177,257,261,274)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:341451"
     Site            order(42,95..97,118..119,121,123,158,274)
                     /site_type="other"
                     /note="putative NAD binding site [chemical binding]"
                     /db_xref="CDD:341451"
     Site            order(173,257,274)
                     /site_type="other"
                     /note="putative metal binding site [ion binding]"
                     /db_xref="CDD:341451"
ORIGIN      
        1 mphnpirvvv gpanyfshpg sfnhlhdfft deqlsravwi ygvraiaaaq tklppafglp
       61 gakhilfrgh csesdvqqla aesgddrsvv igvgggalld takalarrlg lpfvaaptia
      121 atcaawtpls vwyndagqal hyeifddanf mvlvepeiil napqqyllag igdtlakwye
      181 avvlapqpet lpltvrlgin naqairdvll nsseqaladq qnqqltqsfc dvvdaiiagg
      241 gmvgglgdrf trvaaahavh ngltvlpqte kflhgtkvay gilvqsallg qddvlaqltg
      301 ayqrfhlptt laelevdinn qaeidkviah tlrpvesihy lpvtltpdtl raafekvesf
      361 ka