MULTISPECIES: hydroxycarboxylate dehydrogenase HcxA

LOCUS       WP_001120441             362 aa            linear   BCT 16-DEC-2020
            [Enterobacteriaceae].
ACCESSION   WP_001120441
VERSION     WP_001120441.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 362)
  AUTHORS   Sevin,D.C., Fuhrer,T., Zamboni,N. and Sauer,U.
  TITLE     Nontargeted in vitro metabolomics for high-throughput
            identification of novel enzymes in Escherichia coli
  JOURNAL   Nat. Methods 14 (2), 187-194 (2017)
   PUBMED   27941785
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR008059
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..362
                     /gene="hcxA"
     Protein         1..362
                     /product="hydroxycarboxylate dehydrogenase HcxA"
                     /EC_number="1.1.1.-"
                     /calculated_mol_wt=38961
     Region          1..362
                     /region_name="PRK10586"
                     /note="putative oxidoreductase; Provisional"
                     /db_xref="CDD:182570"
     Site            order(42,95..97,100,103,118..119,121,140..141,158,166,173,
                     177,257,261,274)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:341451"
     Site            order(42,95..97,118..119,121,123,158,274)
                     /site_type="other"
                     /note="putative NAD binding site [chemical binding]"
                     /db_xref="CDD:341451"
     Site            order(173,257,274)
                     /site_type="other"
                     /note="putative metal binding site [ion binding]"
                     /db_xref="CDD:341451"
ORIGIN      
        1 mphnpirvvv gpanyfshpg sfnhlhdfft deqlsravwi ygkraiaaaq tklppafglp
       61 gakhilfrgh csesdvqqla aesgddrsvv igvgggalld takalarrlg lpfvavptia
      121 atcaawtpls vwyndagqal hyeifddanf mvlvepeiil napqqyllag igdtlakwye
      181 avvlapqpet lpltvrlgin naqairdvll nsseqalsdq qnqqltqsfc dvvdaiiagg
      241 gmvgglgdrf trvaaahavh ngltvlpqte kflhgtkvay gilvqsallg qddvlaqltg
      301 ayqrfhlptt laelevdinn qaeidkviah tlrpvesihy lpvtltpdtl raafkkvesf
      361 ka