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ribose-phosphate diphosphokinase [Escherichia coli].


LOCUS       WP_001119392             337 aa            linear   BCT 24-FEB-2020
ACCESSION   WP_001119392
VERSION     WP_001119392.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 337)
  AUTHORS   Hove-Jensen,B., Andersen,K.R., Kilstrup,M., Martinussen,J.,
            Switzer,R.L. and Willemoes,M.
  TITLE     Phosphoribosyl Diphosphate (PRPP): Biosynthesis, Enzymology,
            Utilization, and Metabolic Significance
  JOURNAL   Microbiol. Mol. Biol. Rev. 81 (1) (2016)
   PUBMED   28031352
REFERENCE   2  (residues 1 to 337)
  AUTHORS   Willemoes,M., Hove-Jensen,B. and Larsen,S.
  TITLE     Steady state kinetic model for the binding of substrates and
            allosteric effectors to Escherichia coli phosphoribosyl-diphosphate
            synthase
  JOURNAL   J. Biol. Chem. 275 (45), 35408-35412 (2000)
   PUBMED   10954724
REFERENCE   3  (residues 1 to 337)
  AUTHORS   Willemoes,M. and Hove-Jensen,B.
  TITLE     Binding of divalent magnesium by Escherichia coli phosphoribosyl
            diphosphate synthetase
  JOURNAL   Biochemistry 36 (16), 5078-5083 (1997)
   PUBMED   9125530
REFERENCE   4  (residues 1 to 337)
  AUTHORS   Hove-Jensen,B., Harlow,K.W., King,C.J. and Switzer,R.L.
  TITLE     Phosphoribosylpyrophosphate synthetase of Escherichia coli.
            Properties of the purified enzyme and primary structure of the prs
            gene
  JOURNAL   J. Biol. Chem. 261 (15), 6765-6771 (1986)
   PUBMED   3009477
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011247
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..337
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..337
                     /gene="prs"
     Protein         1..337
                     /product="ribose-phosphate diphosphokinase"
                     /EC_number="2.7.6.1"
                     /calculated_mol_wt=36518
     Region          26..336
                     /region_name="PRK01259"
                     /note="ribose-phosphate diphosphokinase"
                     /db_xref="CDD:234929"
ORIGIN      
        1 mpgphsfrqi lstngrmpev llvpdmklfa gnatpelaqr ianrlytslg daavgrfsdg
       61 evsvqinenv rggdifiiqs tcaptndnlm elvvmvdalr rasagritav ipyfgyarqd
      121 rrvrsarvpi takvvadfls svgvdrvltv dlhaeqiqgf fdvpvdnvfg spilledmlq
      181 lnldnpivvs pdiggvvrar aiakllndtd maiidkrrpr anvsqvmhii gdvagrdcvl
      241 vddmidtggt lckaaealke rgakrvfaya thpifsgnaa nnlrnsvide vvvcdtipls
      301 deikslpnvr tltlsgmlae airrisnees isamfeh