MULTISPECIES: SPI-2 type III secretion system effector E3 ubiquitin

LOCUS       WP_001115840             788 aa            linear   BCT 10-SEP-2020
            transferase SspH2 [Salmonella].
ACCESSION   WP_001115840
VERSION     WP_001115840.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 788)
  AUTHORS   Quezada,C.M., Hicks,S.W., Galan,J.E. and Stebbins,C.E.
  TITLE     A family of Salmonella virulence factors functions as a distinct
            class of autoregulated E3 ubiquitin ligases
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 106 (12), 4864-4869 (2009)
   PUBMED   19273841
REFERENCE   2  (residues 1 to 788)
  AUTHORS   Haraga,A. and Miller,S.I.
  TITLE     A Salmonella enterica serovar typhimurium translocated leucine-rich
            repeat effector protein inhibits NF-kappa B-dependent gene
            expression
  JOURNAL   Infect. Immun. 71 (7), 4052-4058 (2003)
   PUBMED   12819095
REFERENCE   3  (residues 1 to 788)
  AUTHORS   Miao,E.A. and Miller,S.I.
  TITLE     A conserved amino acid sequence directing intracellular type III
            secretion by Salmonella typhimurium
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 97 (13), 7539-7544 (2000)
   PUBMED   10861017
REFERENCE   4  (residues 1 to 788)
  AUTHORS   Miao,E.A., Scherer,C.A., Tsolis,R.M., Kingsley,R.A., Adams,L.G.,
            Baumler,A.J. and Miller,S.I.
  TITLE     Salmonella typhimurium leucine-rich repeat proteins are targeted to
            the SPI1 and SPI2 type III secretion systems
  JOURNAL   Mol. Microbiol. 34 (4), 850-864 (1999)
   PUBMED   10564523
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR000675
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..788
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..788
                     /gene="sspH2"
     Protein         1..788
                     /product="SPI-2 type III secretion system effector E3
                     ubiquitin transferase SspH2"
                     /calculated_mol_wt=87092
     Region          1..788
                     /region_name="PRK15387"
                     /note="type III secretion system effector E3 ubiquitin
                     transferase SspH2"
                     /db_xref="CDD:185285"
     Region          205..222
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275378"
     Region          284..303
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          344..362
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          384..403
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          404..427
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          447..464
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275378"
ORIGIN      
        1 mpfhigsgcl patisnrriy riawsdtppe msswekmkef fcsthqteal eciwtichpp
       61 agttredvin rfellrtlay agweesihsg qhgenyfcil dedsqeilsv tlddagnytv
      121 ncqgysethr ltldtaqgee gtghaegasg tfrtsflpat tapqtpaeyd avwsawrraa
      181 paeesrgraa vvqkmracln ngnavlnvge sglttlpdcl pahittlvip dnnltslpal
      241 ppelrtlevs gnqltslpvl ppgllelsif snplthlpal psglcklwif gnqltslpvl
      301 ppglqelsvs dnqlaslpal pselcklway nnqltslpml psglqelsvs dnqlaslptl
      361 pselyklway nnrltslpal psglkelivs gnrltslpvl pselkelmvs gnrltslpml
      421 psgllslsvy rnqltrlpes lihlssettv nlegnplser tlqalreits apgysgpiir
      481 fdmagasapr etralhlaaa dwlvparege papadrwhmf gqednadafs lfldrlsete
      541 nfikdagfka qisswlaqla edealrantf amateatssc edrvtfflhq mknvqlvhna
      601 ekgqydndla alvatgremf rlgkleqiar ekvrtlalvd eievwlayqn klkkslglts
      661 vtsemrffdv sgvtvtdlqd aelqvkaaek sefrewilqw gplhrvlerk apervnalre
      721 kqisdyeety rmlsdtelrp sglvgntdae rtigarames akktfldglr plveemlgsy
      781 lnvqwrrn