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LOCUS WP_001114533 269 aa linear BCT 05-JUL-2022 glycosylase/DNA-(apurinic or apyrimidinic site) lyase [Enterobacteriaceae]. ACCESSION WP_001114533 VERSION WP_001114533.1 KEYWORDS RefSeq. SOURCE Enterobacteriaceae ORGANISM Enterobacteriaceae Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales. COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: NF002211.1 Evidence Source :: NCBI Protein Cluster (PRK) Source Identifier :: PRK01103 ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..269 /organism="Enterobacteriaceae" /db_xref="taxon:543" gene 1..269 /gene="mutM" Protein 1..269 /product="bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase" /EC_number="3.2.2.23" /EC_number="4.2.99.18" /GO_function="GO:0003676 - nucleic acid binding [Evidence IEA]" /GO_function="GO:0003684 - damaged DNA binding [Evidence IEA]" /GO_function="GO:0003906 - DNA-(apurinic or apyrimidinic site) endonuclease activity [Evidence IEA]" /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]" /GO_function="GO:0008534 - oxidized purine nucleobase lesion DNA N-glycosylase activity [Evidence IEA]" /GO_function="GO:0016799 - hydrolase activity, hydrolyzing N-glycosyl compounds [Evidence IEA]" /GO_function="GO:0019104 - DNA N-glycosylase activity [Evidence IEA]" /GO_process="GO:0006281 - DNA repair [Evidence IEA]" /GO_process="GO:0006284 - base-excision repair [Evidence IEA]" /calculated_mol_wt=30129 Region 1..269 /region_name="PRK01103" /note="bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase" /db_xref="CDD:234899" ORIGIN 1 mpelpevets rrgiephlvg atilhavvrn grlrwpvsee iyrlsdqpvl svqrrakyll 61 lelpegwiii hlgmsgslri lpeelppekh dhvdlvmsng kvlrytdprr fgawlwtkel 121 eghnvlahlg peplsddfng eylhqkcakk ktaikpwlmd nklvvgvgni yaseslfaag 181 ihpdrlassl slaecellar vikavllrsi eqggttlkdf lqsdgkpgyf aqelqvygrk 241 gepcrvcgtp ivatkhaqra tfycrqcqk