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MULTISPECIES: recombinase family protein [Enterobacteriaceae].


LOCUS       WP_001102876             208 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_001102876
VERSION     WP_001102876.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 208)
  AUTHORS   Stark,W.M.
  TITLE     The Serine Recombinases
  JOURNAL   Microbiol Spectr 2 (6) (2014)
   PUBMED   26104451
REFERENCE   2  (residues 1 to 208)
  AUTHORS   Keenholtz,R.A., Rowland,S.J., Boocock,M.R., Stark,W.M. and
            Rice,P.A.
  TITLE     Structural basis for catalytic activation of a serine recombinase
  JOURNAL   Structure 19 (6), 799-809 (2011)
   PUBMED   21645851
REFERENCE   3  (residues 1 to 208)
  AUTHORS   Rice,P.A.
  TITLE     Resolving integral questions in site-specific recombination
  JOURNAL   Nat Struct Mol Biol 12 (8), 641-643 (2005)
   PUBMED   16077726
REFERENCE   4  (residues 1 to 208)
  AUTHORS   Smith,M.C. and Thorpe,H.M.
  TITLE     Diversity in the serine recombinases
  JOURNAL   Mol Microbiol 44 (2), 299-307 (2002)
   PUBMED   11972771
REFERENCE   5  (residues 1 to 208)
  AUTHORS   Hallet,B. and Sherratt,D.J.
  TITLE     Transposition and site-specific recombination: adapting DNA
            cut-and-paste mechanisms to a variety of genetic rearrangements
  JOURNAL   FEMS Microbiol Rev 21 (2), 157-178 (1997)
   PUBMED   9348666
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10132949
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..208
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     Protein         1..208
                     /product="recombinase family protein"
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence
                     IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /calculated_mol_wt=23494
     Region          3..148
                     /region_name="SR_Res_par"
                     /note="Serine recombinase (SR) family, Partitioning
                     (par)-Resolvase subfamily, catalytic domain; Serine
                     recombinases catalyze site-specific recombination of DNA
                     molecules by a concerted, four-strand cleavage and
                     rejoining mechanism which involves a transient...;
                     cd03767"
                     /db_xref="CDD:239736"
     Site            order(8,10,71..72,75)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:239736"
     Site            10
                     /site_type="active"
                     /note="catalytic nucleophile [active]"
                     /db_xref="CDD:239736"
ORIGIN      
        1 mnvriycras tegqhadral tslrefsksk gwqiageyie nasgaklerv elmrllseaq
       61 sgdlllveai drlsrlehsa wvelkdtlnr kgliivsmdl ptswqmvema gndltsgilr
      121 avnamlidil atmarqdyet rrkrqqqgie raksegiyig raknqearei vremleqgvk
      181 pelimkaagi sratyyrikn ellivkse