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MULTISPECIES: class II fumarate hydratase [Enterobacteriaceae].


LOCUS       WP_001099102             467 aa            linear   BCT 03-JUN-2024
ACCESSION   WP_001099102
VERSION     WP_001099102.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00979.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..467
                     /gene="fumC"
     Protein         1..467
                     /product="class II fumarate hydratase"
                     /EC_number="4.2.1.2"
                     /GO_component="GO:0045239 - tricarboxylic acid cycle
                     heteromeric enzyme complex [Evidence IEA]"
                     /GO_function="GO:0004333 - fumarate hydratase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006106 - fumarate metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=50331
     Region          1..464
                     /region_name="fumC"
                     /note="fumarate hydratase; Reviewed; PRK00485"
                     /db_xref="CDD:234779"
     Site            order(98,100,126,129..132,139..141,188,324,326,331)
                     /site_type="active"
                     /db_xref="CDD:176465"
     Site            order(186..189,193,199..200,206,210,214,232,262..263,266,
                     269..270,272,275..276,279,282..283,286..287,289..290,
                     293..294,344,352,355..357,410)
                     /site_type="other"
                     /note="tetramer interface [polypeptide binding]"
                     /db_xref="CDD:176465"
ORIGIN      
        1 mntvrsekds mgaidvpadk lwgaqtqrsl ehfristekm ptslihalal tkraaakvne
       61 dlgllseeka sairqaadev lagqhddefp laiwqtgsgt qsnmnmnevl anrasellgg
      121 vrgmerkvhp nddvnksqss ndvfptamhv aallalrkql ipqlktltqt lseksrafad
      181 ivkigrthlq datpltlgqe isgwvamleh nlkhieyslp hvaelalggt avgtglnthp
      241 eyarrvadel avitcapfvt apnkfealat cdalvqahga lkglaaslmk iandvrwlas
      301 gprcgigeis ipenepgssi mpgkvnptqc ealtmlccqv mgndvainmg gasgnfelnv
      361 frpmvihnfl qsvrlladgm esfnkhcavg iepnrerinq llneslmlvt alnthigydk
      421 aaeiakkahk egltlkaaal algylseaef dswvrpeqmv gsmkagr