MULTISPECIES: MFS transporter [Salmonella].

LOCUS       WP_001095738             413 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_001095738
VERSION     WP_001095738.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 413)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 413)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 413)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13023689
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     Protein         1..413
                     /product="MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=43787
     Region          25..398
                     /region_name="MFS_SLC46_TetA_like"
                     /note="Eukaryotic Solute carrier 46 (SLC46) family,
                     Bacterial Tetracycline resistance proteins, and similar
                     proteins of the Major Facilitator Superfamily of
                     transporters; cd17330"
                     /db_xref="CDD:340888"
     Site            order(32..33,36..37,40,72,122..123,125..127,130,149,
                     152..153,156,227,230..231,234..236,239,272,276,326..327,
                     331,335,351,354..355,358..359,362)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340888"
ORIGIN      
        1 mntnvyentd setitplnkr rilpvfllvg lyaastaavm svlpfyirem ggspliigii
       61 iateafsqfc aaplighlsd rvgrkriliv tlaiaaisll llanaqcilf illartlfgi
      121 sagnlsaaaa yiadcthvrn rrqaigiltg ciglggivga gvsgwlsris lsapiyaafi
      181 lvlgsalvai wglkdpstts rttdkiaafs arailkmpvl rvliivmlch ffaygmyssq
      241 lpvflsdtfi wnglpfgpka lsyllmadgv inifvqlfll gwvsqyfser kliilifall
      301 ctgfltagia ttipvlvfai vcisiadala kptylaalsv hvsparqgiv igtaqaliai
      361 adfispvlgg fvlgyalygv wigiaisvai iglvtamiyl skssvlivkp ete