MULTISPECIES: BREX-1 system adenine-specific DNA-methyltransferase

LOCUS       WP_001095591            1225 aa            linear   BCT 05-MAY-2024
            PglX [Salmonella].
ACCESSION   WP_001095591
VERSION     WP_001095591.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 1225)
  AUTHORS   Goldfarb,T., Sberro,H., Weinstock,E., Cohen,O., Doron,S.,
            Charpak-Amikam,Y., Afik,S., Ofir,G. and Sorek,R.
  TITLE     BREX is a novel phage resistance system widespread in microbial
            genomes
  JOURNAL   EMBO J 34 (2), 169-183 (2015)
   PUBMED   25452498
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF033452.1
            Evidence Source    :: NCBIFAM
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1225
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..1225
                     /gene="pglX"
     Protein         1..1225
                     /product="BREX-1 system adenine-specific
                     DNA-methyltransferase PglX"
                     /EC_number="2.1.1.72"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /calculated_mol_wt=141208
     Region          6..1210
                     /region_name="BREX_1_MTaseX"
                     /note="BREX-1 system adenine-specific
                     DNA-methyltransferase PglX; NF033452"
                     /db_xref="CDD:468037"
ORIGIN      
        1 mntnnikkya pqarnqfrda viqklttlgi sadkkgnlqi adaelvgetm rygqfdypks
       61 tltrrdrlvk rareqgfdvl vehcaytwfn rlcairymei hgyldhgfhm lshpdnptgf
      121 evldhvpeva eallpekkaq lvemklsgnq deaiyrelll aqchalhram pflfeavdde
      181 aelllpdnlt rtdsilrglv dgipeedwqe vevigwlyqf yisekkdavi gkvvksedip
      241 aatqlftpnw ivqylvqnsv grqwlqtypd splkgkmdyy iepaeqtpev qaqlaaitpa
      301 siepesikvl dpacgsghil ievynvlkni yeergyrard ipqlilenni fgldiddraa
      361 qlsgfallmm arqddrrift rdvrlnivsl qeslhldiak lwqqlnfhqq nqtgsmgdmf
      421 aentalahtd saeyqllmrt lkrfvnaktl gsliqvpqee eaelkaflea lyrmeqegdf
      481 qqkaaakafi pyiqqawila qrydavvanp pymggkgmns elkefaknnf pdskadlfam
      541 fmqnafsllk engfnaqvnm qswmflssye alrnwlldnk tfitmahlga rafgqisgev
      601 vqttawvikn qhseryqpvf frlidgreev kksdlllrkn ifdkftqhdf knipgmpiay
      661 widlpsllsf rhhkklgeki alkagmstgd nikfqrywye vsikktlitn kesntkidih
      721 nikwfpcssg geyrkwygnn eivvnwenng yeirnfkfen gktrsavrnd eyyfregitw
      781 skisqgnfcv ryrpkgfvfd dtgrcgfsnn knellyaagl mctpvvnhyl silaptlsft
      841 sgelasvpyp eiedeiielv tnaieiaknd wdsqeqswdy vcspllehns tqllrniykq
      901 kintniklve tlllientin nifidklqld ktiikavlqs eitllcnpny rykniqdhtd
      961 ltnkyytdit idilsyiigc mmgrysldre glvyahegnk gfaelvaeda yktfpadndg
     1021 ilplmddewf dddvtsrvke fvrtvwgeeh lqenlefiae slclyaikpk kgesaldtir
     1081 rylstqfwkd hmkmykkrpi ywlfssgkek afeclvylhr yndatlarmr teyvvpllar
     1141 yqanidrlne qvdgasggea trlkrerdsl skkfnelrsf ddrlrhyadm risidlddgv
     1201 kvnygkfgdl ladvkaitgn apeii